心脏起搏与肌钙蛋白Ⅰ水平变化的研究  

Correlation Between Cardiac Pacing and the Change in the Level of cTnI

作　　者：向真[1] 张翼[1] 

机构地区：[1]湖南师范大学第一附属医院心内科,湖南长沙410005

出　　处：《中外医疗》2016年第7期40-42,共3页China & Foreign Medical Treatment

摘　　要：目的 探讨患者术前及术后的c Tn I水平、c Tn I阳性发生率。方法整群收集2014年1月—12月在该院心内科行抗缓慢型心律失常人工心脏起搏器、心功能(NYHA)分级Ⅱ级以下的患者54例,用酶联免疫试剂盒分别测量患者术前、术后1 d、术后1周的c Tn I水平及c Tn I阳性发生率。结果 c Tn I阳性发生率为38.89%,术前、术后1 d、术后1周的c Tn I水平分别为(4.67±0.60)ng/m L、(6.63±0.80)ng/m L、(4.67±0.60)ng/m L,术前与术后1 d相比,差异有统计学意义(P<0.05),但术后1周与术前相比差异无统计学意义(P>0.05)。结论抗缓慢型心律失常人工心脏起搏器对心肌造成微小损害,在术后1周时c Tn I水平可恢复在正常范围内。Objective To investigate the preoperative and postoperative level of c Tn I and c Tn I positive rate. Methods 54 cases with below grade Ⅱ cardiac function classification by NYHA underwent the implantation of anti-bradyarrhythmia artificial cardiac pacemaker in Department of Cardiology in our hospital from January 2014 to December 2014 were selected.ELISA kits were used to measure the level of c Tn I before surgery, 1 day after surgery, and 1 week after surgery and the c Tn I positive rate was calculated. Results The c Tn I positive rate was 38.89%. The level of c Tn I was（4.67 ± 0.60） ng/m L,（6.63 ± 0.80） ng/m L,（4.67 ± 0.60） ng/m L before surgery, 1 day after surgery and 1 week after surgery, respectively. The difference in the c Tn I level was statistically significant before surgery and 1 day after surgery（P〈0.05）, but that was not statistically significant 1 week after surgery and before surgery（P0.05）. Conclusion The implantation of anti-bradyarrhythmia artificial cardiac pacemaker caused minor damage to the myocardium; the level of c Tn I might recovered to the normal range1 week after surgery.

关 键 词：心脏起搏 心肌 心律失常 肌钙蛋白 

分 类 号：R541.7[医药卫生—心血管疾病]