An efficient synthesis of bis(indolyl)methanes and N,N'-alkylidene bisamides by Silzic under solvent free conditions  

作　　者：Hanan A.Soliman Ahmed Y.Mubarak Saad S.Elmorsy 

机构地区：[1]Photochemistry Department,National Research Centre [2]Chemistry Department,Faculty of Science,Mansoura University

出　　处：《Chinese Chemical Letters》2016年第3期353-356,共4页中国化学快报（英文版）

基　　金：Financial support by National Research Center(Cairo,Egypt)

摘　　要：An operationally simple and green method for the synthesis of a wide range of bis（indolyl）methanes,and N,N＇-alkylidene bisamides under mild conditions,with excellent yields using Silzic,has been developed.This improved method furnishes in good yields bis（indolyl）methanes derivatives starting from indole and aldehydes,or ketones,and N,N＇-alkylidene bisamides derivatives starting from acetamide and aldehydes.The catalytic system was reused up to three times with the same efficiency.An operationally simple and green method for the synthesis of a wide range of bis（indolyl）methanes,and N,N＇-alkylidene bisamides under mild conditions,with excellent yields using Silzic,has been developed.This improved method furnishes in good yields bis（indolyl）methanes derivatives starting from indole and aldehydes,or ketones,and N,N＇-alkylidene bisamides derivatives starting from acetamide and aldehydes.The catalytic system was reused up to three times with the same efficiency.

关 键 词：Bis（indolyl）methanes N N＇-alkylidenebisamides Acetamide Mild conditions Silzic 

分 类 号：O621.3[理学—有机化学]