肠内营养在重症应激性高血糖患者支持治疗中的应用  

Enteral Nutrition Support in Patients with Severe Irritable Hyperglycemia

作　　者：罗爱花 黄文静[2] 周锦扬[2] 倪穗琴[3] 张晨[3] 

机构地区：[1]惠州市第六人民医院药学部,广东惠州516211 [2]广州市第一人民医院营养科,广东广州510180 [3]广州市第一人民医院药学部,广东广州510180

出　　处：《今日药学》2016年第3期181-183,共3页Pharmacy Today

基　　金：广东省医院药学研究基金(2013YY04)

摘　　要：目的对比自制高能膳和能全力对应激性高血糖患者血糖的影响。方法选择神经外科ICU住院的重症患者40例,随机分成高能膳组和能全力组,胃肠道适宜的情况尽早开始,连续支持10 d。观察2组患者治疗期间的血糖变化及胃肠道反应情况。结果 12组患者在给予肠内营养支持后,患者血糖均有所下降,但均未能控制平稳,高能膳组患者肠内营养后第4天与第7天、第7天与第10天间患者空腹静脉血糖有显著性差异(P<0.05);能全力组患者肠内营养后第4天与第7天间患者空腹静脉血糖有显著性差异(P<0.05);2给予肠内营养期间未出现明显胃肠道反应。结论本研究结果提示,自制高能膳对神经外科重症应激性高血糖患者血糖的控制有一定的效果,但是对于血糖波动方面控制欠佳。OBJECTIVE To compare the effect of Gaonengshan with nutrision on blood glucose of patients with stress hyperglycemia. METHODS A total of 40 patients treated in Neurosurgery ICU were randomly divided into 2 groups： Gaonengshan group（ n = 20）,and nutrision group（ n = 20）. The 2 groups were given energy supply as early as the Gastrointestinal function possible.The trial period was 10 d. RESULTS 1The FBG of patients in both 2 groups was not steady. In the Gaonengshan group,the FBG of4,7,and 10 d after EN had difference comparing with the FBG of EN（ P〈0.05）. While in the nutrision group,their FBG of 4 d,7 d after EN had some difference comparing with the FBG of EN（ P 〈0. 05）. 2 The 2 group patients had little obvious gastrointestinal adverse drug reaction. CONCLUSION The results suggest that Gaonengshan have certain effect on controlling the blood glucose of patients with stress hyperglycemia in Neurosurgery intensive,besides the glycemic undulation.

关 键 词：应激性高血糖 危重症患者 肠内营养 

分 类 号：R97[医药卫生—药品]