基于中医传承辅助系统的治疗胃癌方剂组方规律分析  

Analysis on Composition Rules of Prescriptions for Gastric Cancer by Using Traditional Chinese Medicine Inheritance Support System

作　　者：刘恭喜 邓来军[2] 李有杰[1] 曹晓靖 刘泽旺[1] 孙长岗[2] 

机构地区：[1]山东中医药大学,山东济南250355 [2]潍坊市中医院肿瘤一科,山东潍坊261041

出　　处：《山东中医药大学学报》2016年第1期6-10,共5页Journal of Shandong University of Traditional Chinese Medicine

摘　　要：目的:分析《肿瘤方剂大辞典》中收载的治疗胃癌方剂的组方规律。方法 :应用中医传承辅助系统,收集、整理《肿瘤方剂大辞典》中治疗胃癌的方剂,采用软件集成的数据挖掘方法,对筛选出治疗胃癌的方剂进行组方规律分析。结果:共有248个治疗胃癌的方剂符合纳入要求,收录药物414味,出现频次≥15药物32味,以白术、陈皮、茯苓等行气健脾、清热散结药物为主,支持度≥15药物组合有39个,关联规则(支持度≥15,置信度≥0.7)11条,演化出包括石见穿-白英-白花蛇舌草、白术-甘草-人参等46个核心组合,新处方23个。结论:明确了《肿瘤方剂大辞典》中治疗胃癌方剂的组方规律,主要为益气健脾、理气散结。Objective：To analyze the composing rules prescriptions for treating gastric cancer collected in Dictionary of tumor prescriptions. Methods：Using traditional Chinese medicine inheritance support system（TCMISS） to collect and sift the prescriptions for treating gastric cancer in the dictionary,then enter into the TCMISS one by one,by using the excavation method from the integration of the software to analyze composing rules of the collected prescriptions. Results：There were 248 prescriptions for treating gastric cancer up to the collection standards,including 414 herbs. For frequency ≥15,there were 32 herbs,including Rhizoma Atractylodis Macrocephalae,pericarpium citri reticulatae,Poria cocos,which had effects of promoting Qi and invigorating spleen,clearing heat and removing stasis. Based on support ≥15,there were 39 herbs combination. Based on 11 association rules（support≥15 and confidence≥0.7）,we involved 46 core combinations,such as salvia chinensis-solanum lyratum-Oldenlandia diffusa,Rhizoma Atractylodis Macrocephalae-liquorice-ginseng,and achieved 23 new prescriptions. Conclusion：The rules of treating gastric cancer were comfirmed,which were invigorating spleen and replenishing Qi,invigorating stasis by regulating Qi.

关 键 词：中医传承辅助系统 胃癌 肿瘤方剂大辞典 组方规律 

分 类 号：R273.52[医药卫生—中西医结合]