肛周脓肿多重耐药菌分布及耐药性分析  

Distribution of Multi-drug Resistant Microorganisms in Perianal Abscess, and an Analysis of their Drug-resistance

作　　者：秦中国[1] 张学辉[1] 卢艳[1] 王青[1] 沈永杰[1] 王宏梅[1] 

机构地区：[1]大庆油田总医院肛肠科,黑龙江大庆163000

出　　处：《中国肛肠病杂志》2016年第2期45-47,共3页Chinese Journal of Coloproctology

摘　　要：为探讨肛周脓肿多重耐药菌（MDRMs）分布及耐药情况，选择2014年6月至2015年10月收治的138例肛周脓肿患者进行研究，手术切开脓肿留取脓液行细菌培养，采用VITEK-Ⅱ做菌种鉴定及药敏试验。结果显示，138例肛周脓肿患者中，有32例患者分离出MDRMs43株，感染率为21．7％（32／138）。其中大肠埃希菌占51．1％（22／43），铜绿假单胞菌占23．2％（10／43），肺炎克雷伯菌占16．3％（7／43）；大肠埃希菌对氨苄西林、头孢哌酮、头孢噻肟及环丙沙星耐药率较高，铜绿假单孢菌对氨苄西林、阿莫西林／克拉维酸、头孢唑林、头孢噻肟耐药率较高，肺炎克雷伯菌对氨苄西林100％耐药。结果表明，肛周脓肿MDRMs以革兰阴性菌为主，临床应根据药敏试验结果合理选用或调整用药，有效控制其产生和传播。In order to investigate the distribution of the multi-drug resistant microorgnism（MDRMs） ,and drug-resistant status,authors selected 138 cases of perianal abscess who admitted in coloproctological dept. （2014-06--2015-10） as research objects,operationally incised abscess to take out pus for bacterial culture, then made bacteria specimen identification and drug-sensitivity test by the method of VITEK-Ⅱ.As results,in 138 cases 43 strains MDRMs were isolated from 32 cases, infection rate was 21.7% （32/138）, a- mong which E.coli. accounted for 51.1 % （22/43） and presented higher rate of drug-resistance to Ampicil- lin, Cefoperazone, Cefotaxime and Ciprofloxacin, Pseudomonas aeruginosa for 23.2 % （10/43） and to Ampicillin, Amoxicillin/Clavulanie acid, Cefazolin, Cefotaxine, Kleb siella pn eumoinae for 16.3 % （7/43） and to Ampicillin even up to 100%.Results show that in MDRMs of perianal abscess G- bacteria remains pre- dominated ; it should be rationally to choose drugs or to adjust the use of drugs, and effectively to control their production and spread according to the results of drug-sensitivity test.

关 键 词：肛周脓肿 多重耐药菌 抗菌药物 

分 类 号：R657.15[医药卫生—外科学]