Tp-e/QT比值对急性ST段抬高心肌梗死患者介入治疗的预后价值  

Prognostic value of Tp-e/QT ratio in patients with ST-segment elevation myocardial infarctionundergoing primary percutaneous coronary intervention

作　　者：贺文奇[1] 赵香梅[1] 楚英杰[1] 杨蕾[1] 

机构地区：[1]河南省人民医院,河南郑州450003

出　　处：《中国民康医学》2016年第6期11-12,50,共3页Medical Journal of Chinese People’s Health

基　　金：河南省科技攻关项目:急性心肌梗死院前溶栓的可行性及安全性研究(省科技厅122102310156)

摘　　要：目的:探讨Tp-e/QT比值与急性ST段抬高心肌梗死初始经皮冠状动脉介入治疗(PCI)患者预后评估的关系。方法:分别测算118例首次发生急性ST段抬高心肌梗死患者介入治疗前(pre-PCI)和介入治疗后(post-PCI)的心电图Tp-e和Tp-e/QT的比值。结果:介入治疗前后,患者的Tp-e/QT比值分别为0.29(95%CI 0.24-0.32)和0.23(95%CI 0.22-0.27),两者具有明显差异,P=0.0001;高pre-PCI Tp-e/QT比值与患者心梗后死亡率增高相关,其界值为0.29;介入治疗后QT和校正的QT(QTc)较介入前增大(QT:407 vs 421ms,P<0.0001)。结论:pre-PCI Tp-e/QT比值可预测ST段抬高心肌梗死患者行PCI的全因死亡可能性,且QT在PCI后增大。Objective To explore and evaluate relationship between Tp-e/ QT ratio and prognosis of patients with ST-segmentelevation myocardial infarction （STEMI） after primary percutaneous coronary intervention （pPCI）. Methods： The Tp-einterval andTp-e/ QT ratio before and after the intervention were measured and calculated for 180 Patients with first-time STEMI and treated withpPCI. Results： The pre- and post-PCI Tp-e/ QT ratio were 0. 29 （95%CI, 0. 24-0. 32） and 0. 23 （95%CI, 0. 22-0. 27）, respectively, and the difference was significant （P =0. 0001）. A higher pre-PCI Tp-e/ QT ratio was associated with increased mortality （thecutoff value of 0. 29）. After the intervention, the uncorrected QT and heart rate-corrected QT intervals were prolonged after PCI （QT：407 vs 421 milliseconds, P〈0. 0001）. Conclusions： In the patients with STEMI undergoing pPCI, the pre-PCI Tp-e/ QT ratio maypredict the subsequent all-cause mortality, and the QT interval increases after the procedure.揖

关 键 词：TP-E间期 ST段抬高心肌梗死 经皮冠状动脉介入治疗 Tp-e/QT比值 预后 

分 类 号：R542.22[医药卫生—心血管疾病]