PET/CT与CT在重型创伤性脑损伤的显像对比研究  

Comparative research of PET/CT and CT imaging in severe traumatic brain injury

作　　者：尹延庆[1] 岑学程 王东[2] 龙霄翱[1] 李捷[1] 黄梓雄[1] 廖壮槟 

机构地区：[1]广东医学院附属医院神经外科,524001 [2]广东医学院附属医院核医学科,524001

出　　处：《中国实用医药》2016年第7期14-15,共2页China Practical Medicine

摘　　要：目的研究比较在重型创伤性脑损伤(TBI)患者的诊断过程中,正电子发射计算机断层显像(PET)/CT和CT的诊断价值。方法回顾性分析21例车祸致重型TBI的非手术患者的临床资料,对比评价PET/CT和CT在重型TBI伤后的脑组织形态结构和功能代谢状态的显像作用效果。结果经影像学检查后,21例患者中,采用PET/CT检查发现阳性病灶[脑挫裂伤和(或)脑缺血]78.25处,明显多于使用CT检查所示阳性病灶61.25处,PET/CT检查阳性病灶部位敏感度高于CT检查,差异有统计学意义(P<0.01);经PET/CT检测出的大脑皮层和(或)皮层下区域阳性病灶部位及脑深部区域阳性病灶部位敏感度均高于CT检测出的病灶,差异有统计学意义(P<0.01)。结论 PET/CT对重型TBI患者较CT的临床诊断价值更高。Objective To research and compare diagnostic value of positron emission computed tomography（PET）/CT and CT in diagnosis of severe traumatic brain injury（TBI） patients. Methods A retrospective analysis was made on clinical data of 21 nonsurgical patients with severe TBI. Comparative evaluation was made on imaging effects between PET/CT and CT in brain tissue form structure and functional metabolic state after severe TBI. Results After imaging examination, PET/CT detected more positive lesion [cerebral contusion and（or） cerebral ischemia] as 78.25 parts than 61.25 parts by CT. PET/CT showed higher sensitivity in detection of positive lesion than CT, and the difference had statistical significance（P〈0.01）. PET/CT also showed higher sensitivity in detection of cerebral cortex and（or） subcortical region positive lesion and cerebral deep positive lesion than CT, and their difference had statistical significance（P〈0.01）. Conclusion PET/CT provides higher clinical value in clinical diagnosis of severe TBI patients than CT.

关 键 词：创伤性脑损伤 正电子发射计算机断层显像 

分 类 号：R651.15[医药卫生—外科学]