86例先天性心脏病合并肺动脉高压产妇所产新生儿资料分析  

Clinical Analysis of 86 Cases of Neonatal of Pregnancy Complicated Congenital Heart Disease with Pulmonary Hypertension

作　　者：许冀闽[1] 苏瑛[1] 刘桂英[1] 

机构地区：[1]首都医科大学附属北京安贞医院儿科,北京市100029

出　　处：《中国病案》2016年第4期52-54,共3页Chinese Medical Record

摘　　要：目的通过分析86例先天性心脏病(CHD)合并肺动脉高压(PH)孕妇所生产新生儿临床资料,探讨孕妇CHD合并PH对新生儿的影响。方法回顾性分析2003年1月至2013年10月收治的86例CHD合并PH产妇所生新生儿的临床资料,同时选取同期妊娠合并CHD不伴有PH的孕妇所生83例新生儿、以及同期孕检正常无妊娠合并症的孕妇的135例新生儿为对照组,分析比较三组新生儿出生体重、身长,以及早产儿、小于胎龄儿(SGA)、窒息的发生率。采用SPSS17.0统计软件进行统计学分析。结果 86例CHD合并PH孕妇新生儿平均出生体重、身长、早产儿发生率、SGA发生率、新生儿窒息发生率,同83例妊娠合并CHD不伴有PH的孕妇所生新生儿平均出生体重、身长、早产儿发生率、SGA发生率、新生儿窒息发生率,以及同期孕检正常无妊娠合并症的孕妇的135例新生儿平均出生体重、身长、早产儿发生率、SGA发生率、新生儿窒息发生率比较有统计学差异(P<0.05)。孕妇PH分级:轻度35例(40.7%),中度21例(24.4%),重度30例(34.9%)。CHD合并PH的孕妇中PH轻度组、中度组、重度组新生儿出生体重、身长,三组间比较具有统计学意义(P<0.05)。结论 CHD合并PH孕妇所生产的新生儿,出生体重和身长低于正常孕妇新生儿,而且低于CHD不伴有PH孕妇的新生儿;CHD伴PH孕妇其早产儿、SGA、新生儿窒息的发生率均明显升高;尤其CHD合并重度PH孕妇的新生儿窒息、SGA的发生率明显增多。Objective To investigate the possible effect of pregnancy complicated congenital heart disease（CHD）with pulmonary hypertension（PH） on the neonatal. Methods 86 offspring of pregnancy complicated CHD with PH were admitted in Anzhen hospital from January,2003 to October, 2013. Retrospectively analyzed the clinical date of newborn infants,included birth weight,birth height,infant premature,small for gestational age（SGA） and neonatal asphyxia. 83 offsprings of pregnancy complicated CHD without PH and 135 offsprings of pregnancy without complication were selected as control group during the same period. All clinical date were analyzed by statistic analysis. Results The average birth weight,birth height, infant premature,SGA, neonatal asphyxia of 86 infant newborn of 86 pregnant women complicated CHD with PH were significantly different between birth weight,birth height,infant premature,SGA, neonatal asphyxia of 83 infant newborn of pregnant women complicated CHD without PH and 135 infant newborn of pregnant women without complication. Pregnant women with grade I PH were 35 cases（40.7%）, grade II PH were 21 cases（24.4%）, grade III PH were 30 cases（34.9%）.The average birth weight,birth height of pregnant women complicated CHD with grade I PH, grade II PH, grade III PH were significantly different（P〈0.05）. Conclusions The average birth weight,birth height of neonatal of pregnant women complicated CHD with PH were lower than common infant newborn, and lower than infant newborn of pregnant women complicated CHD without PH. The incidence of infant premature,SGA,neonatal asphyxia of pregnant women complicated CHD with PH were higher than common infant newborn. The incidence of neonatal asphyxia and SGA of pregnant women complicated CHD with grade III PH were higher.

关 键 词：妊娠 先天性心脏病 肺动脉高压 新生儿 

分 类 号：R722.1[医药卫生—儿科]