Minor Compounds from Fungus Ganoderma cochlear  

作　　者：Man Dou Rong-tao Li Yong-xian Cheng 

机构地区：[1]Kunming University of Science and Technology, Kunming 650500, China [2]State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China

出　　处：《Chinese Herbal Medicines》2016年第1期85-88,共4页中草药（英文版）

基　　金：NSFC-Joint Foundation of Yunnan Province(U1202222);National Natural Science Foundation of China(21472199);a project from State Key Laboratory of Phytochemistry and Plant Resources in West China;Kunming Institute of Botany(P2013-ZZ03)

摘　　要：Objective To study the chemical constituents of the fungus Ganoderma cochlear. Methods The compounds were isolated by using MCI gel CHP 20P, Sephadex LH-20, RP-18 column chromatography, and preparative TLC. The structures were identified by means of spectroscopic methods. Results Two phenolic normeroterpenoid and meroterpenoid, cochlearols C and D （1 and 2）, together with six benzene derivatives, 3- methoxy-4-hydroxy-phenylethanol （3）, 4-hydroxyacetophenone （4）, p-hydroxycinnamic methyl ester （5）, 2-methoxy-4-hydroxybenzaldehyde （6）, 4-hydroxy-3-methoxy benzoic acid （7）, and 2-hydroxy-5-ethoxybenzoic acid （8）, were isolated from the fruiting bodies of Ganoderma cochlear. Conclusion Compounds 1 and 2 are new phenolic normeroterpenoid and meroterpenoid, respectively.Objective To study the chemical constituents of the fungus Ganoderma cochlear. Methods The compounds were isolated by using MCI gel CHP 20P, Sephadex LH-20, RP-18 column chromatography, and preparative TLC. The structures were identified by means of spectroscopic methods. Results Two phenolic normeroterpenoid and meroterpenoid, cochlearols C and D （1 and 2）, together with six benzene derivatives, 3- methoxy-4-hydroxy-phenylethanol （3）, 4-hydroxyacetophenone （4）, p-hydroxycinnamic methyl ester （5）, 2-methoxy-4-hydroxybenzaldehyde （6）, 4-hydroxy-3-methoxy benzoic acid （7）, and 2-hydroxy-5-ethoxybenzoic acid （8）, were isolated from the fruiting bodies of Ganoderma cochlear. Conclusion Compounds 1 and 2 are new phenolic normeroterpenoid and meroterpenoid, respectively.

关 键 词：Ganoderma cochlear  Ganodermataceae phenolic meroterpenoid 

分 类 号：R284[医药卫生—中药学]