健康促进对中风后轻度认知障碍患者认知功能的干预作用观察  

Observation on the Impact of Health Promotion on Mild Cognitive Impairment Induced by Stroke

作　　者：贾蓓[1] 金香兰[2] 张志辰[2] 郑宏[2] 张允岭[2] 

机构地区：[1]北京中医药大学,北京100029 [2]北京中医药大学东方医院,北京100078

出　　处：《世界中医药》2016年第1期22-28,共7页World Chinese Medicine

基　　金：2010年中医药行业科研专项(编号:201007002);北京中医药大学研究创新团队项目(编号:2011-CXTD-23);2011年北京市科技计划项目(编号:Z111107056811040)

摘　　要：目的:初步探讨健康促进对中风后轻度认知障碍的干预作用。方法:本研究基于课题组设计的多中心、大样本、平行、随机、对照的试验方案,以中风后轻度认知障碍患者为研究对象,纳入患者873例,随机分为干预组和对照组,干预组给予健康促进+健康教育,对照组给予健康教育,2组随访180 d,观察患者Mo CA评分变化情况。结果:干预180 d后,干预组Mo CA平均分较入组时有改善,且得分改善情况优于对照组(P<0.05)。干预180天后,干预组好转154例(36.2%),平稳156例(36.6%),下降116例(27.2%);对照组组好转111例(24.8%),平稳185例(41.4%),下降151例(33.8%)(P<0.05)。对健康促进各项目及年龄、文化程度做多因素回归分析,显示穴位按摩(P=0.009)、中药泡脚(P=0.011)、体育活动(P=0.000)、社交活动(P=0.000)可进入回归方程。即穴位按摩、中药泡脚、体育活动、社交活动是改善认知功能的保护性因素。结论:健康促进可改善中风后轻度认知障碍患者认知功能水平,其中体育活动、社交活动、穴位按摩、中药泡脚是认知功能的保护性因素。Objective： To observe the impact of health promotion on mild cognitive impairment（ MCI） induced by stroke. Methods： There are a total of 873 cases of patients with MCI induced by stroke who are selected and randomly divided into two groups：intervention group and the control group. The intervention group was given health promotion and health education and the control group was given health education. After 180 d of follow-up,Mo CA score and other changes were observed between the two groups.Results： After intervention,Mo CA score in the intervention group was improved and compare with that of the control group,the differences were statistically significant（ P〈0. 05）. After intervention,there were 154 cases got improved（ 36. 2%）,156 cases remained stable（ 36. 6%）,and 116 cases got worse（ 27. 2%） in the intervention group; while 111 cases got improved（ 24. 8%）,185 cases remained stable（ 33. 8%）,and 151 cases got worse（ 33. 8%） in the control group. The differences between the two groups was sadistically different（ P〈0. 05）. Analysis on the age,eudcation degree of patients shows that massage（ P = 0. 009）,lavipeditum（ P = 0. 011）,physical exercise（ P = 0. 000）,and social action（ P = 0. 000） could be included in regression equation.This means that such factors could assist in the improvement of cognitive function. Conclusion： Health promotion could help patients with MCI to recover,and massage,lavipeditum,physical exercise and social action also make great contribution.

关 键 词：中风后轻度认知障碍 健康促进 临床观察 

分 类 号：R255.2[医药卫生—中医内科学]