平均血小板体积/血小板计数比值对急性ST段抬高型心肌梗死PCI术后院内心脏不良事件的预测作用  

Mean platelet volume/platelet count ratio as a predictor for in-hospital occurance of major adverse cardiac events after acute ST-elevation myocardial infarction with PCI

作　　者：王静[1] 谷云飞[1] 金军[1] 薛书峰[1] 陈剑锋[1] 张守彦[1] 

机构地区：[1]郑州大学附属洛阳中心医院心内科洛阳市心脑血管病研究所,河南省洛阳市471000

出　　处：《中国心血管病研究》2016年第1期45-48,共4页Chinese Journal of Cardiovascular Research

摘　　要：目的 研究平均血小板体积（MPV）和血小板计数（P）比值（MPV/P）对急性ST段抬高型心肌梗死（STEMI）PCI术后院内不良心脏事件的预测价值.方法 回顾分析2014年1月至2015年6月在郑州大学附属洛阳中心医院接受急诊PCI年龄＜75岁的STEMI患者341例,其中符合入选标准的患者共216例.入院时记录所有研究对象的临床资料,检测血常规、心肌损伤标志物等指标,并统计住院期间心脏不良事件（包括急性心衰、心肌再梗死、心源性死亡）的发生例数.将入选研究对象按照MPV值和MPV/P值排序并分别二等分,分为MPV高值组、MPV低值组及MPV/P高值组、MPV/P低值组.结果 STEMI患者中,MPV/P高值组（MPV/P＞32.6）的院内主要心脏不良事件发生率明显高于MPV/P低值组（MPV/P≤32.5）（26％比13％,P＜0.01）;MPV高值组（MPV＞8.4）与MPV低值组（MPV≤8.3）院内主要心脏不良事件发生率差异无统计学意义（21％比18％,P＞0.05）.结论 MPV/P对STEMI患者院内不良心脏事件的发生具有一定的预测价值.Objective To evaluate the prediction value of mean platelet volume/platelet count for in-hos- pital occurrence of major adverse cardiac events after acute ST-elevation myocardial infarction （STEMI） with PCI. Methods In this retrospective study, 341 consecutive patients with STEMI were eligible to be enrolled from Jan- uary, 2014 to June, 2015. Among them 216 patients satisfied the inclusion criteria. Laboratory examinations in- cluding mean platelet volume, platelet count and so on were done. In-hospital occurrence of major adverse cardiac events, including acute heart failure （AHF）, reinfarction and death were investigated. Patients were stratified into equal bisectors according to MPV, and MPV/platelet ratio, higher MPV, lower MPV and higher MPV/P, lower MPV/P. Results In patients with STEMI, MPV/P ratio of group （MPV/P〉32.6） in the incidence of major ad- verse cardiac events was higher than low MPV/P （MPV/P≤32.5）gToup （26% vs 13%, P〈0.01 ）. There was no significantly different between the high ratio of MPV（ MPV〉8.4 ） and MPV low-value groups （MPV ≤ 8.3 ）（ 21% vs 18%, P〉0.01 ）. Conclusion The ratio of MPV/P had a certain predictive value for in-hospital occurrence of ma- jor adverse cardiac events after acute ST-elevation myocardial infarction.

关 键 词：平均血小板体积 血小板计数 ST段抬高型心肌梗死 

分 类 号：R542.22[医药卫生—心血管疾病]