小儿急性上呼吸道感染膏摩方药成型工艺研究  

Study on the Forming Process of the Gao Mo Medicine for Children with Acute Upper Respiratory Infection

作　　者：孙爱清[1] 马涛[1] 高鹏[2] 王琳[2] 

机构地区：[1]山东省肿瘤防治研究院,山东济南250117 [2]山东中医药大学,山东济南250355

出　　处：《山东中医杂志》2016年第2期153-155,共3页Shandong Journal of Traditional Chinese Medicine

基　　金：山东省中医药科技发展计划项目(编号:2009-036)

摘　　要：目的 :研究治疗小儿急性上呼吸道感染的中药膏摩制剂银翘凝胶的成型工艺。方法 :采用单因素实验法和正交实验法,以凝胶成型性、样品细腻性、稳定性等为指标进行基质种类及成型工艺优选。结果:实验优选了以2%卡波姆940为凝胶基质,以0.5%吐温-80为增溶剂,以20%甘油为保湿剂进行膏摩方凝胶剂的制备。结论:优选出的成型工艺简单、可行,制备的样品稳定性好。Objective：To study the forming process of traditional Chinese medicine Gao Mo drugs for acute upper respiratory tract infection in children. Methods：Single factor experiment and orthogonal experiment were used to optimize the matrix type and forming process,according to the index of gel forming,refineness,and stability. Results：The optimized recipe was 2% carbomer-940 as the gel matrix,0.5% Twain-80 as solubilizing agent and 20% glycerol as wetting agent. Conclusion：The optimized process is simple and feasible,and the stability of the sample is good.

关 键 词：膏摩方药 银翘凝胶 成型工艺 卡波姆 

分 类 号：R283.6[医药卫生—中药学]