简易乳腺磁共振序列筛选乳腺癌临床可行性研究  

Breast magnetic resonance imaging with abbreviated protocol in detection and diagnosis of breast cancer

作　　者：武靖[1] 郭嘉嘉[2] 王殊[2] 李安琪[1] 康钰[1] 洪楠[1] 王屹[1] 

机构地区：[1]北京大学人民医院放射科,北京100044 [2]北京大学人民医院乳腺中心,北京100044

出　　处：《中国实用外科杂志》2016年第4期437-440,共4页Chinese Journal of Practical Surgery

摘　　要：目的探讨乳腺磁共振简易序列(BMRI-AP)筛选乳腺癌的临床可行性。方法收集2010年5月至2014年12月北京大学人民医院214例经钼靶或超声怀疑乳腺单发结节的女性病人行BMRI检查。以术后病理学检查为金标准,比较BMRI-AP和全扫描序列(BMRI-FDP)筛选乳腺癌的敏感度、特异度、阳性预测值及阴性预测值。结果 BMRI-AP及BMRI-FDP检查及阅读时间分别为5 min,45s及25min,1200s,均检出全部119例乳腺癌。BMRI-AP诊断乳腺癌敏感度(97.5%)及阴性预测值(95.9%)高于BMRI-FDPF(95.8%和94.0%),但差异无统计学意义(P=0.72和P=0.72)。尽管BMRI-AP诊断乳腺癌特异度(73.7%)和阳性预测值(82.3%)低于BMRI-FDP(82.1%和87.0%),但同样差异无统计学意义(P=0.22和P=0.32)。结论 BMRI-AP与BMRI-FDP相比,诊断乳腺癌的敏感度及特异度相似,但检查和阅片时间却显著缩短。BMRI-AP是临床可行筛选乳腺癌的影像学方法。Objective To investigate the feasibility of breast magnetic resonance imaging （BMRI） with an abbreviated protocol （BMRI-AP） in detection and diagnosis of breast carcinoma. Methods A total of 214 patients with single lesion suspected by digital mammograms or ultrasounds admitted from May 2010 to December 2014 in Peking University People ＇ s Hospital were performed BMRI. All patients underwent BMRI-AP and full diagnostic protocol BMRI （BMRI-FDP）. Two radiologists detected and diagnosed breast carcinomas based on criteria of Breast Imaging Reporting and Data System （BI-RADS） . Sensitivity, specificity, positive predictive value （PPV） and negative predictive value （NPV） of BMRI-AP and BMRI-FDP were analyzed and compared. Results Both BMRI-AP and BMRI-FDP could detect 119 breast carcinomas that were confirmed by pathological analyses. The imaging acquisition and interpretation time of BMRI-AP and BMRI-FDP were 5rain, 45s and 25min, 1200s, respectively. The ability of BMRI-AP and BMRI-FDP in determination of breast carcinoma were shown as sensitivity of 97.5% and 95.8%, specificity of 73.7% and 82.1%, PPV of 82.1% and 87.0%, and NPV of 95.9% and 94.0%, respectively. But there was no statistical significance （P=0.72, P= 0.22, P=0.32, P=0.72）. Conclusion BMRI-AP with shorter acquisition time and interpretation time has similar sensitivity and specificity in detection and diagnosis of breast cancer compared with BMRI-FDP. BMRI-AP is demonstrated as one of efficient imaging tool in screening breast carcinoma.

关 键 词：筛查 乳腺癌 磁共振 磁共振简易序列 

分 类 号：R6[医药卫生—外科学]