SPECT-MRI异机融合图像在烟雾病中的应用价值初探  

A preliminary study of SPECT-MRI fusion imaging by different machine in patients with moyamoya disease

作　　者：张林悦 弓健[1] 郭斌[1] 唐勇进[1] 尚靖杰[1] 徐浩[1] 

机构地区：[1]暨南大学附属第一医院核医学科,广东广州510630

出　　处：《暨南大学学报（自然科学与医学版）》2016年第2期177-180,共4页Journal of Jinan University(Natural Science & Medicine Edition)

基　　金：广东省医学科研基金项目(A201519)

摘　　要：目的:分析烟雾病(MMD)的单光子发射计算机断层成像(SPECT)、磁共振成像(MRI)图像及SPECTMRI异机融合图像,探讨SPECT-MRI异机融合图像在烟雾病中的应用价值.方法:回顾性分析符合烟雾病诊断标准的5例MMD患者的99mTc-ECD脑血流灌注SPECT显像及头颅MRI检查并影像资料,总结其SPECT-MRI影像的特征性表现.结果:SPECT显示额、颞、顶、枕叶放射性稀疏缺损区,脑血流灌注减少;MRI可清晰显示MMD患者的脑实质损害表现(脑梗死、脑出血、脑软化及脑萎缩);SPECT-MRI融合图像显示3例SPECT显示脑血流灌注减低区和MRI显示脑实质损害区是同一部位,SPECT-MRI二者病灶显示匹配;2例SPECT显示脑血流灌注减低区,而相应区域的MRI显示脑实质正常,SPECT-MRI二者病灶显示不匹配.结论:SPECT-MRI融合图像能直观显示烟雾病患者脑实质解剖上的损害及脑血流灌注情况.Aim：The images of SPECT, MRI, and the SPECT-MRI fusion imaging of Moyamoya dis- ease （MMD） were analyzed and the values of SPECT-MRI fusion imaging in MMD were investigated. Methods ： Five cases of patients with MMD were reviewed, which were in accordance with the diagnostic standard. The images of SPECT and MRI and their characteristics of SPECT-MRI fusion imaging wene analyzed. Results： SPECT can show radioactive sparseness areas in frontal lobe, temporal lobe, parietal lobe, occipital lobe. These areas indicate a reduction of cerebral perfusion; MRI can show the lesions clearly in brain parenchymal, such as the cerebral infarction, hemorrhage, encephalomalacia, brain atro- phy. SPECT-MRI fusion imaging shows that the regions of cerebral blood flow perfusion defect in SPECT are the same with the regions of brain damage showed in MRI in three patients, and these lesions match. However, the regions of cerebral blood flow perfusion defect showed in SPECT are normal in MRI, SPECT-MRI shows that these lesions do not match. Conclusion：SPECT-MRI fusion imaging can show brain damage on the anatomy and cerebral blood perfusion clearly.

关 键 词：烟雾病 单光子发射计算机断层成像 磁共振成像 异机融合 

分 类 号：R445.5[医药卫生—影像医学与核医学]