神经内科患者感染耐碳青霉烯类鲍氏不动杆菌的危险因素分析  

Risk factors and preventive measures for neurology patients infected with carbapenem-resistant Acinetobacter baumannii

作　　者：杨钰[1] 王洁[1] 郑莹莹[1] 路海娟[1] 吕红叶 

机构地区：[1]南阳市中心医院神经介入科,河南南阳473000

出　　处：《中华医院感染学杂志》2016年第7期1471-1473,共3页Chinese Journal of Nosocomiology

基　　金：河南省自然科学基金资助项目(hn2817162)

摘　　要：目的探讨神经内科患者耐碳青霉烯类鲍氏不动杆菌感染危险因素,以降低感染率。方法回顾性分析2010年1月-2012年1月118例神经内科患者临床资料,对其中耐碳青霉烯类鲍氏不动杆菌感染患者进行危险因素分析,数据采用SPSS 13.0软件进行统计分析。结果 118例患者中8例发生耐碳青霉烯类鲍氏不动杆菌感染,感染率为6.78%;多因素分析结果显示,基础疾病、侵入性操作、APACHEⅡ评分、碳青霉烯类抗菌药物使用、抗菌药物应用不规范是感染耐碳青霉烯类鲍氏不动杆菌的独立危险因素(P<0.05);8例患者中死亡1例、6例痊愈、有效1例,住院时间(21.4±10.6)d;实验室指标恢复正常时间为(17.3±5.6)d。结论感染耐碳青霉烯类鲍氏不动杆菌与抗菌药物使用紧密相关,采取综合治疗预后良好。OBJECTIVE To investigate the risk factors for neurology patients infected with carbapenem-resistant Acinetobacter baumannii,in order to reduce infection rates.METHODS A retrospective analysis of the clinical data of 118 cases of neurology patients from Jan.2010 to Jan.2012 were conducted.Risk factors of patients who were infected with carbapenem-resistant Acinetobacter baumannii were analyzed.The results were statistically analyzed by software SPSS 13.0.RESULTS Among the 118 case of patients,8were infected with carbapenem-resistant A.baumannii,and the infected rate was 6.78%.The results of multiple-factor analysis showed underlying diseases,invasive procedures,APACHE score,use of carbapenems,and irregular use of antibiotics were the independent risk factors of infecting with carbapenem-resistant A.baumannii（P〈0.05）.For the 8patients,one died,,six were cured,and one was effective.The average hospital stay was（21.4±10.6）days,and the time for laboratory parameters returning to normal was（17.3±5.6）days.CONCLUSION Carbapenem-resistant A.baumannii is closely related to the application of antimicrobial drug.Comprehensive treatment has favorable prognosis.

关 键 词：神经内科 感染 碳青霉烯类 鲍氏不动杆菌 危险因素 预防对策 

分 类 号：R378.99[医药卫生—病原生物学]