感染性心内膜炎患者临床特征与预后影响因素分析  

Clinical characteristics and influencing factors of prognosis of infective endocarditis

作　　者：张苑[1] 任鹏涛[2] 杨婧[3] 刘婷婷[1] 闫庆辉[2] 张国建[2] 

机构地区：[1]河北医科大学第二医院心电图,河北石家庄050000 [2]河北医科大学第二医院肛肠外科,河北石家庄050000 [3]河北医科大学第二医院心内科,河北石家庄050000

出　　处：《中华医院感染学杂志》2016年第7期1531-1532,1535,共3页Chinese Journal of Nosocomiology

基　　金：国家自然科学基金资助项目(81273600)

摘　　要：目的探讨感染性心内膜炎患者的临床特征及预后影响因素,为提高心内膜炎患者预后提供参考依据。方法回顾性分析2010年1月-2014年12月医院收治的900例感染性心内膜炎患者临床资料,分析患者的临床特征及表现,预后影响因素进行单因素及多因素logistic回归分析,结果采用SPSS 20.0软件进行统计分析。结果 900例感染性心内膜炎患者中有基础心脏疾病患者869例占96.56%;单因素分析显示,人工瓣膜、发热≥39℃、超敏C-反应蛋白≥60mg/L、血红蛋白含量<90g/L、血清白蛋白含量<30g/L、采取手术治疗是影响感染性心内膜炎患者预后的相关因素(P<0.05),多因素logistic回归分析显示,血红蛋白含量<90g/L、血清白蛋白含量<30g/L、采取手术治疗是感染性心内膜炎患者预后的独立影响因素(P<0.05)。结论感染性心内膜炎患者多伴有基础心脏疾病,多数心电图显示正常,血红白蛋白、血清白蛋白水平及手术治疗为患者预后影响因素。OBJECTIVE To investigate the clinical characteristics and prognostic factors of infective endocarditis,so as to provide basis for improving the prognosis of patients with endocarditis.METHODS A total of 900 patients with infective endocarditis in the hospital from Jan.2010 to Dec.2014 were selected,and their clinical data were retrospectively analyzed.Clinical characteristics of the patients and their performance were analyzed.The prognostic factors were analyzed by univariate and multivariate logistic regression analyses,the results were statistically analyzed by using SPSS 20.0software.RESULTS Totally 869 patients had underlying heart diseases among the900 patients with infective endocarditis,accounting for 96.56%.The univariate analysis showed artificial valve,fever≥39 ℃,hypersensitive C-reactive protein≥60mg/L,hemoglobin90g/L,serum albumin30g/L and surgical treatment were the related prognostic factors（P〈0.05）.The multivariate logistic regression analysis showed that hemoglobin90g/L,serum albumin30g/L and surgical treatment were the independent prognostic factors（P〈0.05）.CONCLUSIONThe results show that most patients with infective endocarditis have underlying heart diseases,the majority of patients have normal ECG.Levels of hemoglobin and serum albumin as well as surgical treatment are prognostic risk factors in infective endocarditis.

关 键 词：感染性心内膜炎 心电图 临床特征 预后 

分 类 号：R542.41[医药卫生—心血管疾病]