胫腓骨开放性骨折患者创口感染的病原学与预防研究  

Etiology and prevention of wound infections in patients with open fractures of tibia and fibula

作　　者：姬永琴[1] 于国军[2] 邹吉锋[2] 万峰格[2] 赵兰兰[2] 

机构地区：[1]河南省洛阳正骨医院脊柱外四科,河南洛阳471002 [2]河南省洛阳正骨医院膝部损伤科,河南洛阳471002

出　　处：《中华医院感染学杂志》2016年第7期1595-1597,共3页Chinese Journal of Nosocomiology

基　　金：河南省科技发展计划基金资助项目(142102310106)

摘　　要：目的调查胫腓骨发生开放性骨折患者创口感染的病原学特点并探究其危险因素,为临床预防与治疗提供参考依据。方法选择2012年6月-2015年8月医院收治553例胫腓骨开放性骨折患者为研究对象,分析病原菌分布及胫腓骨开放性骨折患者创口感染的危险因素,数据采用SASS 20.0软件进行统计分析。结果 553例胫腓骨开放性骨折患者中56例发生感染,感染率为10.13%;共分离出73株病原菌,以革兰阳性菌为主,共41株占56.16%;多因素logistics回归模型显示,骨伤程度严重、治疗间隔时间长、手术时间长、住院时间及联合抗菌药物应用是导致胫腓骨发生开放性骨折患者伤口感染的独立危险因素(P<0.05)。结论针对性加强患者伤口感染的预防和控制,合理使用抗菌药物,降低感染的发生率。OBJECTIVE To investigate the characteristics of etiology of wound infections in patients with open tibiafibula fractures and its risk factors so as to provides reference for clinical prevention and treatment.METHODS A total of 553 patients with open tibia-fibula fractures were selected in our hospital from Jun.2012 to Aug.2015.Distribution of pathogens and risk factors of wound infections in patients with open tibia-fibula open fractures were investigated.Data were analyzed with SPSS20.0.RESULTS A total of 56 patients suffered from open tibia-fibula open fracture（10.13%）.Totally 73 strains of pathogenic bacteria were isolated,including 41 strains of gram-positive bacteria（56.16%）.According to multi-factor logistic regression model,severe fractures,long treatment time interval,length of hospital time,long operation time,and combined antimicrobial application were the independent risk factors of wound infections in patients with open tibia-fibula open fractures.CONCLUSIONPrevention and control measures to reduce incidence of infections should be taken by using antimicrobial agents rationally.

关 键 词：胫腓骨 开放性骨折 创口感染 病原学 危险因素 

分 类 号：R681.8[医药卫生—骨科学]