行IL-2胸腔内注入治疗顽固性气胸的总体效果评价  

Effect of Intrapleural Injection of IL-2 in the Treatment of Intractable Pneumothorax

作　　者：乔桂红[1] 郭令军[1] 张令令[1] 王敬亭[1] 宋凌[1] 余洁[1] 

机构地区：[1]河南省商丘医学高等专科学校内科教研室,476000

出　　处：《中国继续医学教育》2016年第8期146-147,共2页China Continuing Medical Education

摘　　要：目的探讨白细胞介素-2(IL-2)胸腔内注入治疗顽固性气胸的临床效果及应用价值。方法取90例顽固性气胸患者分为两组,治疗组经胸腔闭式引流管胸腔内注入生理盐水40 ml+IL-2 150万IU+2%利多卡因5 ml;对照组经胸腔闭式引流管胸腔内注入生理盐水40 ml+凝血酶1 000 IU+2%利多卡因,评价临床效果及复发情况。结果治疗组平均住院时间、有效率及复发率均优于对照组(P<0.05),比较差异具有统计学意义。结论胸腔闭式引流联合IL-2胸腔内注入治疗顽固性气胸疗效确切,能缩短住院时间,复发率低,住院费用相对较少。Objective Discuss the effect of intrapleural injection of il-2 in the treatment of intractable pneumothorax. Methods Chose 90 patients with intractable pneumothorax and divided into 2 groups, the treatment was injected through thoracic close drainage tube with saline 40 ml ＋ IL-2 15 million IU ＋ 2% lidocaine 5 ml, the control group was injected with saline 40 ml ＋ thrombin 1 000 IU ＋ 2% lidocaine, to evaluate the clinical efficacy and recurrence. Results In treatment group, the average length of stay, efficient and relapse rate were better than the control group（P0.05）, the difference was statistically significant. Conclusion Internal thoracic drainage combined with thoracic injection of IL-2 in the treatment of intractable pneumothorax can shorten the hospital stay, lower the recurrence rate and can lead to relatively low cost of hospitalization.

关 键 词：IL-2 胸腔 顽固性气胸 总体效果 应用价值 

分 类 号：R561.4[医药卫生—呼吸系统]