干扰素雾化吸入治疗呼吸道合胞病毒性毛细支气管炎的临床效果  

The Clinical Effect of Interferon Atomization Inhalation in the Treatment of Respiratory Syncytial Virus Bronchiolitis

作　　者：任文津 廖洋[1] 苏定邦 孟娜娜[1] 

机构地区：[1]肇庆市第二人民医院肇庆市妇幼保健院儿科,广东肇庆526000

出　　处：《汕头大学医学院学报》2016年第1期38-39,共2页Journal of Shantou University Medical College

基　　金：肇庆市科技立项项目(医疗卫生儿科组2015040305序号8)

摘　　要：目的:探讨干扰素雾化吸入治疗呼吸道合胞病毒(RSV)性毛细支气管炎的临床效果。方法:按入院先后将患儿(94例)分为对照组(布地奈德雾化吸入)和观察组(在对照组治疗的基础上+干扰素雾化吸入),每组47例。对比两组疗效及临床症状改善时间等。结果:观察组(93.6%)治疗总有效率明显高于对照组(76.6%)(P<0.05);观察组治疗后临床症状(发热、肺部啰音、喘憋、气促)改善及住院时间均优于对照组,血氧分压及血氧饱和度水平均高于对照组(P<0.05)。结论:干扰素雾化吸入治疗RSV性毛细支气管炎的临床效果显著,安全性高,不良反应少,患儿易于接受。Objective：To explore the clinical effect of interferon atomization inhalation in the treatment of respiratory syncytial virus（RSV）bronchiolitis. Methods：According to the admitted date,94 children with RSV were divided into control（given budesonide aerosol inhalation）and observation（given interferon atomizing inhalation on basis of same therapy as control group）groups,each group of 47 cases. The effects and clinical symptoms improvement time between two groups.were compared Results：The total effective rate in the observation group was 93.6%,76.6% in the control group（P〈0.05）. The clinical symptoms（fever,lung rale,wheeze,dyspnea）improvement time and hospital stay in the observation group after treatment were superior to control group,the blood oxygen partial pressure and oxygen saturation level were higher than those of the control group（P〈0.05）. Conclusion：Interferon atomizing inhalation in the treatment of RSV bronchiolitis has clinically an obvious effect,high safety,less adverse reaction,and being accepted easily by children.

关 键 词：呼吸道合胞病毒 毛细支气管炎 干扰素 

分 类 号：R373.14[医药卫生—病原生物学]