The biomimetic catalytic synthesis of acetal compounds using β-cyclodextrin as catalyst  

作　　者：Daohong Xia Shengjuan Jiang Lantao Li Yuzhi Xiang Lijun Zhu 

机构地区：[1]State Key Laboratory of Heavy Oil Processing, College of Chemical Engineering, China University of Petroleum,Qingdao

出　　处：《Chinese Journal of Chemical Engineering》2016年第1期146-150,共5页中国化学工程学报（英文版）

基　　金：Supported by the National Natural Science Foundation of China(21376265)

摘　　要：Based on the principle of biomimetic catalysis, β-cyclodextrin was applied to the acetalation reaction as a facile and efficient catalyst, and the synthesis was environmentally friendly with atomic economy. The influencing factors of the acetalation reaction e.g. the reaction time, the volume of water-carrying agent,the molar ratio of catalyst to benzaldehyde and the molar ratio of glycol to benzaldehyde had been studied.The yield of benzaldehyde glycol acetal would reach a maximum of 81.3% under the conditions approached.Six of other acetals were also synthesized. Moreover, a plausible reaction mechanism for the formation of acetal had been proposed.Based on the principle of biomimetic catalysis, β-cyclodextrin was applied to the acetalation reaction as a facile and efficient catalyst, and the synthesis was environmentally friendly with atomic economy. The influencing factors of the acetalation reaction e.g. the reaction time, the volume of water-carrying agent,the molar ratio of catalyst to benzaldehyde and the molar ratio of glycol to benzaldehyde had been studied.The yield of benzaldehyde glycol acetal would reach a maximum of 81.3% under the conditions approached.Six of other acetals were also synthesized. Moreover, a plausible reaction mechanism for the formation of acetal had been proposed.

关 键 词：β-Cyclodextrin Biomimetic catalysis Synthesis Acetal 

分 类 号：O621.251[理学—有机化学]