基于动态光散射研究pH值对茄红素胶囊粒径的影响  

Study on the effect of pH value on particle size of lycopene nanocapsules based on dynamic light scattering

作　　者：孙彦清[1] 娄本浊[1] 黄朝军[1] 刘亚锋[1] 

机构地区：[1]陕西理工学院物理与电信工程学院,汉中723000

出　　处：《原子与分子物理学报》2016年第2期240-244,共5页Journal of Atomic and Molecular Physics

基　　金：国家自然科学基金(41105107);陕西省自然科学基础研究计划基金(2012JM5014);陕西省教育厅科学研究计划基金(2013JK0617)

摘　　要：用微乳化技术结合复合团聚法制备了纳米及亚微米茄红素胶囊,基于动态光散射测量分析了环境p H值对胶囊的粒径大小及其分布的影响.结果表明,对纳米茄红素胶囊,当p H值为3.5、6.0及6.8时能稳定的分散,而p H值为7.4时则会出现明显的聚集现象;对亚微米茄红素胶囊,当p H值为3.5、6.0、6.8及7.4时其粒径分布均为双峰状态,其中粒径较大的为亚微米茄红素胶囊,粒径较小的为包覆不良的颗粒,且p H=7.4时的粒径明显小于其它三种p H值时的粒径.虽然亚微米胶囊在p H=7.4时粒径明显变小的结果与纳米胶囊相同,但亚微米胶囊并不像纳米胶囊那样出现聚集现象.Nano and submicron lycopene capsules are prepared by micro- emulsion technology combined with composite reunion method and the effect of pH value on the particle size and its distribution are measured by dy- namic light scattering in this study. The results show that, lycopene nanocapsules can disperse stably at pH = 3.5, 6.0 and 6. 8. There is obvious aggregation at pH = 7.4. The particle size distributions of submicron cap- sules present bimodal state at pH = 3.5, 6. 0, 6. 8 and 7.4 and the size at pH = 7.4 is significantly greater than that of other three pH values. The sizes of submicron capsules and nanocapsules become smaller, but the aggre- gation appeared for nano capsules is not produced for submicron capsules at pH = 7.4

关 键 词：动态光散射 粒径测量 茄红素胶囊 PH值 稳定性 

分 类 号：TQ645.9[化学工程—精细化工]