不对称中位取代卟啉类化合物的研究进展  

Advances in Asymmetric meso-Substituted Porphyrins

作　　者：戴胜平 孔翔飞[1] 王桂霞[1] 夏励婷 刘鹏[1] 余彩莉[1] 

机构地区：[1]桂林理工大学化学与生物工程学院,桂林541004

出　　处：《化学通报》2016年第4期314-320,共7页Chemistry

基　　金：国家自然科学基金项目(11364013);广西教育厅项目(KY2015YB129);桂林理工大学博士启动基金项目资助

摘　　要：卟啉类化合物不仅在自然界中广泛存在,而且在分子自组装、生物仿生、电化学、分析化学、催化化学等诸多领域都具有广泛的应用。卟啉因中位取代基的种类、数量和性质不同,所表现出来的化学性质也不相同,因此引起了有机工作者的广泛关注。本文首先简单地介绍了卟啉类化合物的基本结构特点和物理、化学性质;然后以结构相对简单的四苯基卟啉为对象,讨论了其合成反应机理;接着重点阐述了不对称中位取代卟啉的3种合成方法,即混合缩合法、全合成法和功能化预先形成法;最后对近年来国内外关于卟啉类化合物的研究状况进行了总结,并对其广阔的发展和应用前景进行展望。Porphyrins widely exist in nature and have a wide range of applications in the fields of the molecular self-assembly,biomimicry,electrochemistry,analytical chemistry,catalysis chemistry,and so on. Porphyrins with a variety of meso-substituents show different chemical properties,which have attracted wide attention. In this paper,the structural characteristics,physical and chemical properties of porphyrins were simply introduced firstly. Secondly,the tetraphenyl porphyrin which had relatively simple structures was chosen as example,its reaction mechanism was discussed. Thirdly, three kinds of synthetic methods for asymmetric meso-substituted porphyrins, i. e. mixed condensation synthesis, total synthesis and synthesis of preformed functionalization were described detailedly.Finally,the research progress of porphyrins in recent years was summarized and their development and application in the future were prospected.

关 键 词：不对称卟啉 中位取代 反应机理 合成方法 

分 类 号：O626[理学—有机化学]