南京地区32家医院2012-2014年抗血小板药和抗凝血药使用分析  

Application of Antiplatelet and Anticoagulant Drugs Used in 32 Hospitals of Nanjing in 2012-2014

作　　者：潘海燕[1] 刘慧[1] 许静洁[1] 蔡静[1] 

机构地区：[1]南京大学医学院附属鼓楼医院药学部,南京210008

出　　处：《中国药房》2016年第11期1463-1466,共4页China Pharmacy

摘　　要：目的:为抗血小板药和抗凝血药临床合理使用提供参考。方法:采用回顾性研究方法,对南京地区32家医院2012-2014年抗血小板药和抗凝血药的销售金额、用药频度(DDDs)、日均费用(DDC)等进行统计和分析。结果:南京地区32家医院共涉及23种抗血小板药和抗凝血药,药品销售金额呈逐年增长趋势;销售金额各年均排前3位的是氯吡格雷、低分子肝素和红花;DDDs各年均排前3位的是氯吡格雷、华法林和低分子肝素;华法林、肝素和噻氯匹啶的DDC<10元;氯吡格雷和利伐沙班的B/A值等于或最接近1,西洛他唑、舒洛地特、蚓激酶、华法林、沙格雷酯、脉络舒通、替格瑞洛和噻氯匹啶的B/A值>1。结论:南京地区32家医院2012-2014年抗血小板药和抗凝血药临床应用基本合理,氯吡格雷、华法林、低分子肝素和肝素占主导地位,替格瑞洛、阿哌沙班、达比加群酯的临床应用前景可观。OBJECTIVE：To provide refereuce for rational use of antiplatelet and anticoagulant drugs. METHODS：In retrospective study,the application of antiplatelet and anticoagulant drugs in 32 hospitals from Nanjing area was analyzed statistically in respects of consumption sum,DDDs,DDC,etc. RESULTS：A total of 23 kinds of antiplatelet and anticoagulant drugs were used in32 hospitals from Nanjing area,and consumption sum increased year by year. Top 3 drugs in the list of consumption sum always were clopidogrel,low molecular weight heparin and Carthamus tinctorious. Top 3 drugs in the list of DDDs were clopidogrel,warfarin and low molecular weight heparin. DDC of warfarin,heparin and ticlopidine was less than 10 yuan;B/A values of clopidpgrel and rovarpxabam were equal to or close to 1;On the other hand,the B/A values of cilostazol,sulodexide,PPA,warfarin,sarpogrelate,mailuo shutong,ticagrelor and ticlopidine were all more than 1. CONCLUSIONS：The antiplatelet and anticoagulant drugs are used rationally in 32 hospitals from Nanjing area;clopidogrel,warfarin,low molecular weight heparin and heparin dominated;ticagrelor,apixaban and dabigatran etexilate is promising in the future.

关 键 词：抗血小板药 抗凝血药 用药分析 南京地区 

分 类 号：R973.2[医药卫生—药品] R969.3[医药卫生—药学]