我院药师干预剖宫产术预防使用抗菌药物的回顾性分析  

Retrospective Analysis of Prophylactic Antibacterial Drugs Use of Cesarean Section in Our Hospital by Clinical Pharmacist's Intervention

作　　者：金灿[1] 姚晓燕[1] 朱玲仙[1] 

机构地区：[1]嘉兴市妇幼保健院,浙江嘉兴314051

出　　处：《中国药房》2016年第11期1558-1560,共3页China Pharmacy

基　　金：浙江省医学会临床科研基金项目(No.2013ZYC-B6)

摘　　要：目的：为剖宫产术合理预防使用抗菌药物提供参考。方法：回顾性调查我院2013年1-12月（干预前）手术开始前0.5-2 h给予预防用药的剖宫产术患者472例及2014年1-12月（干预后）钳夹脐带后给予抗菌药物的剖宫产术患者431例,对其抗菌药物使用情况进行统计分析。结果：干预后,预防用药给药时机合理率为100%,选择药物品种合理率从64.41%上升至93.50%,预防用药疗程合理率从50.21%上升至92.11%,用法用量合理率也有了明显改善,与干预前比较差异均有统计学意义（P〈0.05）。干预后,人均抗菌药物费用从（103.25±13.62）元下降至（54.61±27.21）元,人均住院费用从（5 574.8±117.6）元下降至（5 427.4±106.7）元,与干预前比较差异均有统计学意义（P〈0.05）。结论：临床药师通过药学干预,能明显提高剖宫产术预防使用抗菌药物的合理率,使我院抗菌药物使用更加规范、合理。OBJECTIVE：To provide reference for rational prophylactic use of antibacterial drugs in cesarean section. METHODS：Retrospective investigation used in analyzing the use of antibacterial drugs between 472 patients underwent cesarean section0.5-2 h before the operation from Jan to Dec. in 2013 and 431 patients after umbilical cord clamp during cesarean section from Jan.to Dec. in 2014. RESULTS：After intervention,the reasonable rate of the opportunity to use prophylactic antibacterial drugs was100%,the reasonable rate of selected drugs varieties increased from 64.41% to 93.50%,and the rate of reasonable treatment course increased from 50.21% to 92.11%,that of usage and dosage also had a noticeable improvement,with statistical significance compared to before intervention（P〈0.05）. Antibacterial cost per capita decreased from（103.25±13.62）yuan to（54.61±27.21）yuan after intervention,and hospitalization cost per capita decreased from（5 574.8±117.6）yuan to（5 427.4±106.7）yuan,with statistical significance compared to before intervention（P〈0.05）. CONCLUSIONS：Clinical pharmacists can improve the reasonable rate of antibacterial drugs for prophylactic use in cesarean section by pharmaceutical intervention,it can make the use of antibacterial drugs more standardized and reasonable.

关 键 词：剖宫产 抗菌药物 预防用药 合理用药 

分 类 号：R978.1[医药卫生—药品] R969.3[医药卫生—药学]