西北地区重要蜱媒疾病的调查研究  

Study on tick-borne disease in Northwest of China

作　　者：李依萍[1] 庞众多[1] 刘增加[2] 

机构地区：[1]中国人民解放军第一医院检验科,甘肃兰州730030 [2]兰州军区疾病预防控制中心,甘肃兰州730020

出　　处：《中华卫生杀虫药械》2016年第2期180-183,共4页Chinese Journal of Hygienic Insecticides and Equipments

基　　金：全军医学科研"十一五"计划专项课题(编号:08Z003)

摘　　要：目的了解西北地区存在的及可能存在的蜱媒疾病。方法采用布旗法收集地区内的蜱标本进行分子生物学检测;收集当地居民的血清标本,运用血清学方法检测莱姆病、Q热、土拉菌病及无形体病等相关疾病的抗体;收集西北地区内所有相关蜱媒疾病的发病资料,分类整理。结果文献调研显示,西北地区已报道的蜱媒疾病共有7种。在西北地区内共采集蜱标本2 460只,分属11个蜱种;其中304只蜱标本检测发现莱姆病螺旋体、207只感染无形体,75只感染土拉弗菌,200只感染Q热立克次体。除无形体外,其他3种病原体在4个调查点内均存在。采集当地人群血清725份,其中185份血清存在目标抗体,进一步证实调查疾病的存在。结论首次对西北地区内蜱媒疾病进行了较系统的调查,证实多种蜱媒疾病的存在,对西北地区蜱媒疾病的预防控制具有重要意义。Objective To investigate the existing and potential tick-borne diseases from Northwest of China.Methods Literature searching,tick collecting and pathogen detecting. Results A total of 2 460 ticks of 11 species were collected and tested for evidence of Borrelia burgdorferii,Anaplasma phagocytophilum,Coxiella burnetii and Francisella tularensis. Of the tested 2 460 ticks,304,217,75 and 200 ticks harboring DNA of Borrelia burgdorferi,Anaplasma phagocytophilum,Coxiella burnetii and Francisella tularensis,respectively. A total of 725 sera were tested for antibodies of different diseases,185 sera showed positive results. Conclusion Tick-borne disease widely distributes in Northwest China. The results will be helpful for the control and prevention of tick borne disease.

关 键 词：莱姆病螺旋体 Q热立克次体 土拉弗氏菌 蜱 流行病学调查 

分 类 号：R384.4[医药卫生—医学寄生虫学]