鹿复合麻醉剂对鹿血浆肾素-血管紧张素-醛固酮系统的影响  

Effect of compound anesthetic for deer on the renin-angiotensin-aldosterone system in plasma of deer

作　　者：尹柏双[1] 李宇航[1] 王楠[1] 王雪莹[1] 宋永利[1] 付连军[1] 

机构地区：[1]吉林农业科技学院动物科技学院,吉林吉林132101

出　　处：《黑龙江畜牧兽医》2016年第4期187-188,191,共3页Heilongjiang Animal Science And veterinary Medicine

基　　金：国家自然科学基金项目(31302150);吉林省科技厅发展计划项目(20140204062NY);吉林省教育厅"十二五"科学技术项目(吉教科合字2014379);吉林农业科技学院博士启动基金项目(吉农院合字2012307);吉林农业科技学院种子基金项目(吉农院合字2013905)

摘　　要：为了研究在鹿复合麻醉剂作用下鹿血流动力学变化与血浆肾素-血管紧张素-醛固酮系统的相关性,试验选取6只健康成年梅花鹿,肌肉注射鹿复合麻醉剂0.04 m L/kg,注药前及注药后15,30,45,60,75,90,120分钟检测收缩压(SBP)、舒张压(DBP)、平均动脉压(MAP)及心率(HR),并同步采集颈静脉血样测定肾素(PRA)、血管紧张素(AⅡ)、醛固酮(ALD)含量。结果表明:麻醉期PRA、AⅡ和ALD含量的变化与SBP、DBP、MAP变化趋势大致相似,存在着相关性。说明鹿复合麻醉剂引起的肾素-血管紧张素-醛固酮系统的变化参与了鹿血压变化的调节。To study the correlation between the hemodynamic changes in deer and the renin- angiotensin- aldosterone system（ RAAS） in plasma in the effect of compound anesthetic for deer（ CAD）,6 healthy adult deer were selected and administrated with intramuscular injection of0. 04 m L / kg CAD. The systolic blood pressure（ SBP）,diastolic blood pressure（ DBP）,mean arterial pressure（ MAP） and heart rhythm（ HR） were monitored before administration and at 15,30,45,60,75,90,120 min after administration. The blood samples from jugular vein were synchronously collected to determine the contents of rennin（ RPA）,angiotensin（ AⅡ） and aldosterone（ ALD） in plasma. The results showed that the changes of PRA,AⅡ and ALD were similar to those in SBP,DBP and MAP,and correlation among them was found. The results indicate that the changes caused by the CAD in RAAS participate in the regulation of blood pressure changes in deer.

关 键 词：鹿复合麻醉剂 梅花鹿 肾素 血管紧张素 醛固酮 血流动力学 

分 类 号：S857.124[农业科学—临床兽医学]