他汀类药物预防造影剂肾病研究的进展  

Research progress of preventive effects of statins on contrast induced nephropathy

作　　者：李阳[1] 杨胜利[1] 杨勇[1] 魏玉杰[1] 韩滨[2] 刘惠亮[1] 

机构地区：[1]武警总医院心血管内科,北京市100039 [2]武警内蒙古总队医院

出　　处：《心血管康复医学杂志》2016年第2期209-212,共4页Chinese Journal of Cardiovascular Rehabilitation Medicine

摘　　要：造影剂肾病(CIN)是在血管内注射碘造影剂后引起的最主要并发症之一,它可增加患者住院率和死亡率,现已经成为当下医院内获得性急性肾功能衰竭的第三大原因,但其根本发病机制目前尚未完全明确,可能与炎症、氧化应激反应等有关。本文就CIN发生机制及他汀类药物对CIN的预防作用作一综述。Contrast induced nephropathy（CIN）is one of the main complications caused by intravenous iodinated contrast media injection,which can increase hospitalization rate and mortality of patients,and it has become the third main cause of acquired acute renal failure in hospital currently,but its fundamental pathogenesis is still not clear,which is considered to be related to inflammation and oxidative stress response etc.The present article made a review on pathogenesis of CIN and preventive effects of statins on CIN.

关 键 词：造影剂 肾病 他汀类 

分 类 号：R972.6[医药卫生—药品]