输卵管积液超声介入硬化治疗对冻融胚胎移植结局的影响  

Effects of interventional ultrasound sclerotherapy on pregnancy outcomes of the women with hydrosalpinx in the frozen-thawed embryo transfer cycles

作　　者：周云[1] 姜宏[1] 冯翠娥[1] 

机构地区：[1]中国人民解放军第105医院生殖医学中心,合肥230031

出　　处：《生殖与避孕》2016年第4期284-287,298,共5页Reproduction and Contraception

基　　金：南京军区医学科技创新重点课题资助项目;项目号:ZD14

摘　　要：目的:探讨超声介入硬化治疗输卵管积液对冻融胚胎移植(frozen-thawed embryo transfer,FET)周期妊娠结局的影响。方法:回顾性分析输卵管积液的输卵管性不孕接受体外受精-胚胎移植(IVF-ET)未妊娠或未移植且有冷冻胚胎的患者FET周期的临床资料,按积液的处理方式分组:A组(观察组)121个周期,FET前行超声介入硬化治疗;B组(对照组)60个周期,FET前行输卵管近端结扎。结果:A、B组胚胎种植率(20.06%vs 20.63%)、临床妊娠率(40.50%vs38.33%)、流产率(14.29%vs 13.04%)、异位妊娠率(6.12%vs 0.00%)组间差异均无统计学意义(P>0.05)。结论:输卵管积液超声介入硬化治疗可获得与输卵管近端结扎治疗近似的FET临床结局,且简单、经济、基本无创。Objective： To investigate the effects of interventional ultrasound sclerotherapy on the pregnancy outcomes of the women with hydrosalpinx in frozen-thawed embryo transfer （FET） cycles. Methods： The data of 181 FET cycles with tubal infertile women were analyzed retrospectively. All of the 181 cycles with hydrosalpinx under hysterosalpingography （HSG） and ultrasonography were divided into two groups. Group A （study group, 121 cycles） were pretreated with interventional ultrasound sclerotherapy, and group B （control group, 60 cycles） were pretreated with proximal tubal ligation / distal tubal ostomy. Results： There were no significant differences in the embryo implantation rate （20.06% vs 20.63%）, the clinical pregnancy rate （40.50% vs 38.33%）, the abortion rate （14.29% vs 13.04%） and the ectopic pregnancy rate （6.12% vs 0.00%） between groups A and B （P〉0.05）. Conclusion： Interventional ultrasound sclerotherapy could obtain similar pregnancy outcomes as proximal tubal tigation / distal tubal ostomy in FET cycles with the advantage of simple, lower cost and less invasion.

关 键 词：输卵管积液 冻融胚胎移植(FET) 超声介入硬化治疗 妊娠结局 

分 类 号：R714.8[医药卫生—妇产科学]