单操作孔胸腔镜肺癌根治术对患者免疫功能的影响  

Effect of Single-port Video-assisted Thoracoscopic Surgery for Lung Cancer Radical Resection on Immune Function of Patients

作　　者：杨凯云[1] 陈安宁[1] 赵光强[1] 陈小波[1] 雷玉洁[1] 

机构地区：[1]昆明医科大学第三附属医院,云南省肿瘤医院胸外科一病区,云南昆明650118

出　　处：《昆明医科大学学报》2016年第3期67-70,共4页Journal of Kunming Medical University

基　　金：云南省卫生厅科技计划基金资助项目(2014NS002)

摘　　要：目的探讨单操作孔胸腔镜肺癌根治术对患者免疫功能的影响.方法回顾分析2014年1月至2014年11月云南省肿瘤医院胸外科一病区施行的单操作孔胸腔镜肺癌根治术42例和同期开胸肺癌根治术45例.比较2组患者术前和术后3 d免疫功能(T细胞、Th细胞、Ts细胞、NK细胞、CIK细胞、CIKN细胞、TH/TS比值)指标.结果 2组患者均无围手术期死亡,手术时间、术中出血量、胸腔闭式引流管拔管时间无统计学差异(P>0.05);单操作孔胸腔镜组术后疼痛更小,下床活动时间更早,对患者免疫指标影响更小,同开胸组比较有统计学差异(P<0.05).结论同开胸手术比较,单操作孔胸腔镜肺癌根治术能降低手术对患者免疫功能的影响.Objective The study was aimed to analyze the effect of single-port video-assisted thoracoscopic surgery（VATS） for lung cancer radical resection on the immune function of patients. Methods A retrospective analysis was made on the clinical data of 42 patients with lung cancer radical resection by single-port VATS and 45 patients by thoracotomy in the department of thoracic surgery from January 2014 to November 2014. The data of immune function including T,Th,Ts,NK,CIK,CIKN cells and TH/TS were compared between the two groups in the preoperative and postoperative day 3. Results No operative related mortality. There were no statistical differences in the operation time, intraoperative blood loss,and chest closed drainage tube drawing time between the two groups（P〉0.05）. In patients with lung cancer radical resection by single-port VATS, postoperative pain, out-of-bed activity and immune indexes were better than patients by thoracotomy（P〈0.05）. Conclusion The single-port VATS for patients can decrease the impact by lung cancer radical resection.

关 键 词：免疫功能 单操作孔胸腔镜 肺癌根治术 

分 类 号：R655[医药卫生—外科学]