^(99m)Tc-MIBI核素显像与CT在原发性甲状旁腺功能亢进症中的诊断价值  

The diagnostic value of ^(99m)Tc-sestamibi scintigraphy and CT in primary hyperparathyroidism

作　　者：陈正国[1] 刘启榆[1] 陈娇[1] 杨兴[1] 何瑜[1] 

机构地区：[1]绵阳市中心医院放射科,四川绵阳621000

出　　处：《中国临床医学影像杂志》2016年第4期239-242,259,共5页Journal of China Clinic Medical Imaging

摘　　要：目的:通过对术前^(99m)Tc-甲氧异腈(MIBI)核素显像与CT图像分析,探讨分析两者在原发性甲状旁腺功能亢进症中的临床诊断价值。方法:回顾分析经病理证实的38例原发性甲状旁腺功能亢进症患者术前^(99m)Tc-MIBI核素显像和CT影像资料,比较^(99m)Tc-MIBI核素显像、CT、^(99m)Tc-MIBI核素显像与CT联合3种影像学方法对原发性甲状旁腺功能亢进症的诊断灵敏度差异。结果:^(99m)Tc-MIBI核素显像、CT、^(99m)Tc-MIBI核素显像与CT联合3种影像学方法诊断原发性甲状旁腺功能亢进症的灵敏度分别为89.65%、64.00%、93.75%;统计分析显示^(99m)Tc-MIBI核素显像组与CT组、CT组与联合组之间差异有统计学意义,^(99m)Tc-MIBI核素显像与CT联合组灵敏度优于其它两种方法。结论:术前^(99m)Tc-MIBI核素显像与CT对原发性甲状旁腺功能亢进症的评估均是必要的,两者联合应用可提高原发性甲状旁腺功能亢进症的诊断价值。Objective： To explore the clinical value of ^（99m）Tc-sestamibi（MIBI） scintigraphy and CT in the diagnosis of primary hyperparathyroidism. Methods： Retrospectively analyzed the image features of^（99m）Tc-MIBI and CT in 38 patients with primary hyperparathyroidism, which were confirmed by pathology. Comparison of the sensitivity of ^（99m）Tc-MIBI scintigraphy, CT,the combination of the two methods. Results： The sensitivity of ^（99m）Tc-MIBI, CT and the combined methods in diagnosis of primary hyperparathyroidism was 89.65%, 64.00% and 93.75% respectively. There were significant difference between ^（99m）Tc-MIBI and CT, CT and the combination group. The sensitivity of the combination group was superior to the other two methods.Conclusion： Both ^（99m）Tc-MIBI and CT provide important information for the pre-operation evaluation of primary hyperparathyroidism. ^（99m）Tc-MIBI in combination with CT can increase the accuracy of diagnosis of the primary hyperparathyroidism.

关 键 词：甲状旁腺功能亢进症 99M锝甲氧基异丁基异腈 放射性核素显像 体层摄影术 X线计算机 

分 类 号：R582.1[医药卫生—内分泌] R817.4[医药卫生—内科学]