腹部多发伤患者引流液可溶性髓样细胞触发受体检测对腹创伤脓毒症的诊断分析研究  

Detection of soluble medullary triggering receptor cells in drainage of patients with multiple abdominal trauma for diagnosis of abdominal sepsis

作　　者：朱永[1] 李娜[1] 何振扬[1] 陈民科[1] 王华杰[1] 麦叶[1] 

机构地区：[1]海南省人民医院重症医学科,海南海口570311

出　　处：《中华医院感染学杂志》2016年第8期1795-1797,共3页Chinese Journal of Nosocomiology

基　　金：海南省自然科学基金资助项目(814322)

摘　　要：目的研究腹部多发伤患者检测引流液可溶性髓样细胞触发受体(sTREM-1)检测对腹创伤脓毒症的临床诊断价值,为了进一步提高腹部多发伤患者伴有腹创脓毒血症的临床确诊率。方法选取2015年1-9月医院诊治的60例腹部多发伤患者为试验组,同期选取住院治疗的60例胃大部分切除术患者为对照组,同时检测两组患者血浆sTREM-1、血浆降钙素原、C-反应蛋白指标,分析sTREM-1在腹部多发伤患者腹创伤脓毒症中的诊断评价,以提高确诊率,数据采用SPSS 18.0软件进行统计分析。结果试验组患者入院治疗后24、48h及72h sTREM-1浓度值,显著高于对照组;试验组C-反应蛋白以及降钙素原水平,显著高于对照组(P<0.05)。结论腹部多发伤患者定期检测引流液sTREM-1水平能够早期诊断腹创伤脓毒症,且联合其他治疗诊断能够进一步提高患者临床确诊率。OBJECTIVE To study the clinical diagnostic value of detection of soluble medullary triggering receptor cells（sTREM-1）in drainage of patients with multiple abdominal trauma for diagnosis of abdominal traumatic sepsis so as to further improve the clinical diagnostic accuracy of abdominal traumatic sepsis.METHODS Totally 60 patients with multiple abdominal trauma during Jan.to Sep.2015 were selected as the test group and another 60 hospitalized patients undergoing partial gastrectomy during the same period were selected as the control group.Indicators such as sTREM-1,plasma procalcitonin and high-sensitivity C reactive protein were detected for both groups at the same time.The sTREM-1in patients with multiple abdominal trauma was evaluated for diagnosis of abdominal traumatic sepsis to increase the diagnostic accuracy.Data were statistically analyzed by software SPSS18.0.RESULTS The sTREM-1concentration at 24 h,48hand 72 hafter admission was significantly higher in the test group than in the control group.The C-reactive protein（CRP）and procalcitonin（PCT）levels were significantly higher in the test group than in the control group（P〈0.05）.CONCLUSIONRegular detection of sTREM-1levels in the drainage of patients with multiple abdominal trauma can be used for early diagnosis of abdominal traumatic sepsis,and it can further improve the clinical diagnostic accuracy in combination with other treatment and diagnosis.

关 键 词：腹部多发伤 引流液 可溶性髓样细胞触发受体 腹创伤脓毒症 诊断价值 

分 类 号：R641[医药卫生—外科学]