胃癌患者根治术后腹腔感染的调查分析  

Abdominal cavity infections in patients with gastric cancer after radical resection

作　　者：戴丐国[1] 杜义安[1] 俞鹏飞[1] 胡超[1] 杨立涛[1] 张云利[1] 王兵[1] 

机构地区：[1]浙江省肿瘤医院腹部肿瘤外科,浙江杭州310022

出　　处：《中华医院感染学杂志》2016年第8期1798-1800,共3页Chinese Journal of Nosocomiology

基　　金：浙江省卫生医药基金资助项目(2012KYA136)

摘　　要：目的分析胃癌患者根治术后腹腔感染率及其感染病原菌分布和耐药性,为临床治疗提供参考依据。方法选择医院2014年1-12月行根治术治疗的900例胃癌患者为研究对象,回顾性分析其临床资料,调查并发腹腔感染情况及感染病原菌分布和耐药性,数据采用SPSS 13.0软件进行统计分析。结果 900例胃癌患者根治术后腹腔感染35例,感染率为3.89%;检出病原菌66株,以革兰阴性菌为主,共41株占62.12%;大肠埃希菌对左氧氟沙星和氨苄西林等抗菌药物的耐药率较高,均>70.00%;铜绿假单胞菌对头孢噻肟、左氧氟沙星、环丙沙星和氨苄西林等抗菌药物的耐药率较高,耐药率均>58.00%。结论胃癌患者根治术后腹腔感染发生率较高,其感染病原菌主要为革兰阴性菌;应加强病原菌监测,指导临床合理选用抗菌药物,从而提高预防控制效果。OBJECTIVE To investigate distribution and drug resistance of pathogens causing abdominal cavity infections so as to provide reference for clinical treatment.METHODS Totally 900 patients with gastric cancer treating with radical resection in our hospital from Jan.2014 to Dec.2014 were chosen,whose clinical data were retrospectively analyzed.The abdominal cavity infections,distribution and drug resistance of pathogens were investigated.SPSS 13.0was adopted for statistical analysis.RESULTS A total of 35 cases with abdominal cavity infections after radical resection out of 900 cases with gastric cancer were found,and the infection rate was 3.89%.Totally66 strains were identified,and contained 23 strains of gram-positive bacteria（34.85%）,41 strains of gram-negative bacteria（62.12%）and 2strains of fungi（3.03%）.Escherichia coli showed high drug resistance to levofloxacin,ampicillin and clindamycin,and the resistant rates were over 70.00%.Pseudomonas aeruginosashowed high drug resistance to cefotaxime,levofloxacin,ciprofloxacin,and ampicillin,and the resistant rates were all over 58.00%.CONCLUSIONThe incidence rate of abdominal cavity infections in patients with gastric cancer after radical resection was high,and the main pathogens were belonged to gram-negative bacteria.It＇s good for guiding clinical rational use of antibacterials and improving clinical effect of prevention to strengthen the monitoring of pathogens in gastric cancer complicated abdominal cavity infections.

关 键 词：胃癌 根治术 腹腔感染 病原菌 

分 类 号：R656.61[医药卫生—外科学]