伊维菌素原粉急性吸入毒性试验研究  

Acute Inhalation Toxicity Test of Ivermectin Raw Powder

作　　者：胡成云[1] 林师道[1] 纪磊[1] 汪建良[1] 张武[1] 岑江杰[1] 

机构地区：[1]浙江省化工研究院有限公司,杭州310023

出　　处：《中国兽药杂志》2016年第4期48-51,共4页Chinese Journal of Veterinary Drug

摘　　要：对伊维菌素原粉急性吸入毒性进行研究,采用限量试验,设定2000 mg/m3一个剂量组,动式口鼻式染毒,有效染毒时间2 h。结果显示,伊维菌素原粉对雌雄大鼠的急性吸入半数致死浓度(LC50)均大于2089 mg/m3。伊维菌素原粉急性吸入毒性属低毒,该结论为安全使用提供了依据。To study the acute inhalation toxicity of Ivermectin raw powder and provide the basis for safe use,limit test,the dose group was 2000 mg / m3,dynamic nose- only exposure,effective exposure time for 2 h. The results showed that ivermectin raw powder in male and female rats acute inhalation median lethal concentration（ LC50）were more than 2089 mg / m3. The acute inhalation toxicity was low toxicity.

关 键 词：伊维菌素原粉 急性吸入毒性 半数致死浓度 

分 类 号：S859.796[农业科学—临床兽医学]