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作 者:徐红[1] 闵智杰 吕天依 刘文婷[2] 干德康[3]
机构地区:[1]上海中医药大学附属龙华医院,上海200032 [2]上海中医药大学,上海201203 [3]复旦大学附属眼耳鼻喉科医院/上海市视觉损害与重建重点实验室,上海200031
出 处:《上海针灸杂志》2016年第4期395-398,共4页Shanghai Journal of Acupuncture and Moxibustion
基 金:国家自然科学基金项目(30801267);上海市科委研究项目(14401932700)
摘 要:目的观察张仁主任医师针刺治疗原发性视网膜色素变性规范化处方的临床疗效,对针刺治疗该病的疗效进行系统客观的评价,为临床推广运用提供依据。方法收集了自1998年至今接受针刺治疗的原发性视网膜色素变性患者共26例(51眼)。采用自身前后对照的方法,观察针刺治疗3个月后及针刺治疗至今患者的视力、视野、视网膜电图(ERG)和视功能损害眼病患者生存质量量表得分指标的变化,并进行临床疗效评定。结果经治后患者的视力和生存质量量表得分与治疗前相比差异均有统计学意义(P<0.05);视野检查中,平均敏感度与治疗前相比差异具有统计学意义(P<0.05),平均缺损与治疗前比较差异无统计学意义(P>0.05);ERG治疗前后比较差异无统计学意义(P>0.05);临床总有效率为69.6%;患者基础视力与疗效评定呈正相关性(P<0.05),患眼病程及年龄与疗效呈负相关性(P<0.05)。结论针刺治疗对原发性视网膜色素变性患者具有一定疗效,同时能提高患者生存质量,并且患眼病程越短,基础视力越好,治疗效果越好。Objective To observe the clinical efficacy of acupuncture by chief physician ZHANG Ren in treating primary pigmentary degeneration of retina(PPDR)based on a standardized formula,for objectively evaluating the efficacy of acupuncture for this disease and providing evidence for promotion in clinic.Method Twenty-six PPDR patients(51 eyes)had been collected ever since the year 1998.By using self-comparison method,the vision,visual field,electroretinogram(ERG),and Quality of Life(QOL)Scale for Patients with Visual Function Damage were observed after 3-month treatment and currently,and the clinical efficacies were evaluated.Result The vision and QOL scores were significantly changed after treatment(P〈0.05);the examination of visual field showed significant difference in average sensitivity(P〈0.05),but insignificant change in average defect(P〉0.05);there was no significant change in ERG(P〉0.05);the total effective rate was 69.6%;the basic vision had a positive correlation with the therapeutic efficacy(P〈0.05),while the disease duration and age had a negative correlation with the therapeutic efficacy(P〈0.05).Conclusion Acupuncture has a certain therapeutic efficacy in treating PPDR and it can enhance the QOL of the patients;a shorter disease duration and better basic vision may predict a higher therapeutic efficacy.
分 类 号:R246.82[医药卫生—针灸推拿学]
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