不同频率电针对帕金森病肌僵直的影响  

Effect of Electroacupuncture at Different Frequencies on Muscle Rigidity in Parkinson's Disease

作　　者：王晓颖[1] 张海峰[2] 李立红[3] 毋振华[4] 

机构地区：[1]浙江中医药大学,杭州310053 [2]浙江中医药大学附属第一医院,杭州310006 [3]浙江省人民医院望江山院区,杭州310024 [4]浙江省立同德医院,杭州310012

出　　处：《上海针灸杂志》2016年第4期413-415,共3页Shanghai Journal of Acupuncture and Moxibustion

基　　金：浙江省中医药管理局课题(2010ZA024)

摘　　要：目的通过与口服多巴丝肼片(美多芭)对照评价2 Hz/100 Hz电针和100 Hz电针对帕金森病(PD)肌僵直的影响。方法将91例帕金森病患者随机分为药物组31例、电针1组(2 Hz/100 Hz组)30例、电针2组(100 Hz组)30例。电针1组、电针2组分别是在药物组治疗基础上配合2 Hz/100 Hz电针、100 Hz电针治疗。运用统一帕金森病评分量表(UPDRS)和肌张力评定量表(TAS)于治疗前、治疗30 d、治疗90 d及180 d回访时进行评分。结果组内UPDRS、TAS评分比较,电针2组在治疗30 d、90 d时均无统计学意义,在180 d回访时具有统计学意义(P<0.01);电针1组及药物组在治疗30 d时均无统计学意义,在90 d及180 d回访时均具有统计学意义(P<0.01)。与药物组比较,电针2组在治疗90 d及180 d回访时均具有统计学意义(P<0.01);电针1组在治疗30 d、90 d、180 d回访时差异无统计学意义(P>0.05)。结论 100 Hz电针配合药物治疗在改善PD患者肌僵直方面疗效优于2 Hz/100 Hz电针配合药物治疗及单纯口服药物治疗。Objective To evaluate the effect of electroacupuncture respectively at 2 Hz/100 Hz and 100 Hz on muscle rigidity in Parkinson＇s disease（PD）by comparing it to oral administration of Levodopa and Benserazide Hydrochloride tablets.Method Ninety-one PD patients were randomized into a medication group of 31 cases,electroacupunture group 1（2 Hz/100 Hz）of 30 cases and electroacupuncture group 2（100 Hz）of 30 cases.Electroacupuncture group 1 and 2 were respectively intervened by electroacupuncture at 2 Hz/100 Hz and 100 Hz in addition to the treatment given to the medication group.The Unified Parkinson＇s Disease Rating Scale（UPDRS）and TAS were evaluated prior to intervention,after 30-day treatment,90-day treatment,and in the 180-day follow-up study.Result Compared to that before intervention,the UPDRS and TAS scores were insignificantly changed after 30-day and 90-day treatment,but significantly changed in the 180-day follow-up study（P〈0.01）in electroacupuncture group 2;the UPDRS and TAS scores were insignificantly changed after 30-day treatment,but significantly changed after 90-day treatment and in the 180-day follow-up study（P〈0.01）in electroacupuncture group 1 and the medication group.Compared to that of the medication group after 90-day treatment and in the 180-day follow-up study,the UPDRS and TAS scores of electroacupuncture group 2 were significantly different（P〈0.01）;the UPDRS and TAS scores of electroacupuncture group 1 were insignificantly different from that of the medication group after 30-day treatment,90-day treatment,and in the 180-day follow-up study（P〉0.05）.Conclusion Compared to electroacupuncture at 2 Hz/100 Hz plus medication and medication alone,electroacupuncture at 100 Hz plus medication can produce a better therapeutic efficacy in improving muscle rigidity of PD.

关 键 词：帕金森病 肌痉挛 电针 频率 针药并用 

分 类 号：R246.6[医药卫生—针灸推拿学]