UPOINT临床表型分类法在慢性前列腺炎/慢性盆底疼痛综合征诊治中应用研究  

Application of UPOINT system in the treatment of chronic prostatitis

作　　者：秦素 江永浩[1] 付招伦[1] 陈孝彬[1] 曾铁兵[1] 雷星辉 刘咏松[1] 王万东[1] 

机构地区：[1]宜宾市第二人民医院泌尿男科,四川宜宾644000

出　　处：《中国男科学杂志》2016年第2期8-12,共5页Chinese Journal of Andrology

基　　金：四川省宜宾市重点科技项目(2014SF014)

摘　　要：目的探讨UPOINT临床表型分类法在慢性前列腺炎/慢性盆底疼痛综合征(CP/CPPS)患者诊治中的应用价值。方法收集2013年10月至2015年5月C2P/CPPS患者186例,随机分为UPOINT治疗组(简称治疗组)和对照组,每组93例,分别按照传统的慢性前列腺炎分类法(1995年美国国立卫生研究院NIH标准)和UPOINT表型分类法(2012年美国)对患者进行分类和治疗,再采用美国NIH慢性前列腺炎症状评分(NIH-CPSI)评估两组患者的治疗效果。结果本组患者中,有排尿症状120人(64.5%),心理症状95人(51.1%),神经症状74人(39.8%),肌痛症状45人(24.2%),器官特异症状28人(15.1%),感染症状21人(11.3%),51%患者自诉有不同程度性功能障碍,90%的患者同时具有超过一项阳性分型,仅11人(5.9%)只有一项阳性分型,且阳性分型数目越多,CPSI评分越高,临床症状越重;治疗6周后,治疗组NIH-CPSI的降低程度比对照组更为显著,差异有显著的统计学意义(P<0.05)。结论 UPOINT表型分类法对于提高慢性前列腺炎的诊疗效果具有显著的意义。Objective To explore the clinical value of UPOINT classification in the treatment of chronic prostatitis （CP）. Methods From Oct 2013 to May 2015, 186 patients with cP/cPPs and 93cases were recruited in the study and they were randomly divided into the treatment group and the control group each based on the traditional classification of chronic prostatitis （the us national institutes of health NIH 1995 standard） and UPOINT phenotypic taxonomy （2012 us）, International chronic prostate inflammatory score （CPSI） was used to evaluate treatment effect of patients in two groups. Results Of all the patients, 120 cases had urinary symptoms （64.5%）, 95 cases psychological symptoms （51.1%）, 74 cases neurologic symptoms（39.8%）, 45 cases tenderness symptoms （24.2%）, 28 cases organ specific symptoms （15.1%）, 21 cases infection symptoms （11.3%）. 51%patients had different degrees of sexual dysfunction, and 90% had more than one positive type at the same time, only 11 cases（5.9%） with only one positive type. Furthermore, the more positive type numbers, the higher the CPSI scores, the heavier clinical symptoms. After 6 weeks of treatment, the NIH-CPSI scores of UPOINT group remarkably decreased compared with those in the control group. Conclusion UPO1NT phenotypic taxonomy shows a significance in improving treatment efficacy of chronic prostatitis.

关 键 词：前列腺炎 盆底疼痛综合征 UPOINT表型分类法 

分 类 号：R697.33[医药卫生—泌尿科学]