右美托咪定用于气管异物取出术麻醉效果评价  

Evaluation of the Effects of Dexmedetomidine on Pediatric Tracheobronchial Foreign Body Removal Surgery

作　　者：曾涟[1] 蒋卓汛[1] 肖志凌[1] 阳丽云[1] 刘敬臣[1] 

机构地区：[1]广西医科大学第一附属医院,广西南宁530021

出　　处：《中国医学创新》2016年第11期4-7,共4页Medical Innovation of China

基　　金：广西壮族自治区卫生厅自筹经费科研课题(Z2013008)

摘　　要：目的:探讨右美托咪定用于小儿气管异物取出术麻醉效果。方法:选择本院急诊行气管异物取出术的患儿50例,随机分为对照组和试验组,每组25例,分别在全麻诱导前10 min内静脉输注氯化钠溶液或右美托咪定(0.5μg/kg)。术中用丙泊酚和瑞芬太尼诱导和维持麻醉。记录入手术室时(T0)、置支气管镜前1 min(T1)、置支气管镜时(T2)、置支气管镜后1 min(T3)、退支气管镜时(T4)的HR、BP和Sp O2,术中丙泊酚和瑞芬太尼用量,术后呛咳、躁动、呕吐等的发生例数和苏醒时间等。结果:两组间各时间点HR、MAP、Sp O2比较无差异(P>0.05)。与对照组比较,试验组手术过程中丙泊酚和瑞芬太尼用量减少(P<0.05),术后呛咳、躁动、呕吐等的发生例数减少(P<0.05)。两组苏醒时间比较差异无统计学意义(P>0.05)。结论:在气管异物取出术中,右美托咪定能减少丙泊酚和瑞芬太尼的用量,术后苏醒质量好。Objective：To investigate the application of Dexmedetomidine to the pediatric tracheobronchial foreign body removal surgery,and observe the anesthetic effects.Method：Fifty children undergoingtracheobronchial foreign body removal surgery were randomly divided into two groups：control group and experimental group.Two groups receiving intravenous infusion of normal saline and Dexmedetomidine 0.5 μg/kg respectively within 10 min before the induction of anesthesia.Propofol and Remifentanil were used during the induction and maintenance of anesthesia.HR,BP and Sp O2 at the time of enter the operating room,1 min before,the moment and 1 min after bronchoscopy inserted,bronchoscopy extract were recorded.The dosage of propofol and remifentanil were counted.Incidence rate of postoperative bucking,restlessness and vomiting were recorded.Measured the recovery time.Result：There were no significant differences in HR,BP and Sp O2 between the two groups at each time point（P〉0.05）.Compared with control group,the dosage of Propofol and Remifentanil in experimental group were smaller（P〈0.05）,incidence rate of postoperative bucking,restlessness and vomiting were smaller（P〈0.05）.There was no significant difference in the recovery time between the two groups（P〉0.05）.Conclusion：In the surgery of removing foreign body in trachea,Dexmedetomidine can reduce the dosage of propofol and remifentanil, the quality of postoperative recovery is good.

关 键 词：右美托咪定 气管异物 儿童 

分 类 号：R614[医药卫生—麻醉学]