中国银屑病患者合并代谢综合征患病率的Meta分析  

Mata analysis on the prevalence of metabolic syndrome in patients with psoriasis in China

作　　者：蔡云飞[1] 吴严[1] 高兴华[1] 

机构地区：[1]中国医科大学附属第一医院皮肤科,辽宁沈阳110000

出　　处：《临床和实验医学杂志》2016年第7期639-642,共4页Journal of Clinical and Experimental Medicine

摘　　要：目的通过Meta分析了解我国银屑病患者合并代谢综合征的流行现状,为早期防治提供科学依据。方法检索Pub Med、中国期刊全文数据库(CNKI)、维普数据库(VIP)及万方数据资源系统(Wanfang database)收录的有关中国地区银屑病患者合并代谢综合征患病率研究的相关文献。采用Stata 12.0软件进行数据合并估算患病率,采用线性回归法(Egger's tests)评价发表偏倚,通过排除其中任意一篇文献对合并效应值的影响进行敏感性分析。结果结果共纳入文献23篇,样本总量6 015例,银屑病患者合并代谢综合征1 477例,银屑病患者合并代谢综合征患病率经分析合并效应量为29%[95%CI(22%,35%)],与亚洲国家相似,但低于西方国家。结论中国银屑病患者合并代谢综合征患病率高达29%,应引起医护人员的高度重视。Objective To evaluate the present situation of metabolic syndrome in patients with psoriasis in China. Methods Literature reviews had been conducted to collect studies on the prevalence of metabolic syndrome in patients with psoriasis in Pubmed,China National Knowledge（ CNKI）,Chinese science and technology journal database（ VIP） and Wanfang database. All data were analyzed by Stata 12. 0 software after evaluation. Sensitivity analysis had been performed to evaluate the stability. Results A total of 23 studies,including a total size of 6015 cases and 1477 patients with metabolic syndrome,were eligible for inclusion in this review. The prevalence of metabolic syndrome by analyzing the effect size was 29%[95CI（ 22%,35%） ],which was close to those of Asian countries and lower than those of western countries. Conclusion The prevalence rate of metabolic syndrome in patients with psoriasis in China is 29%,which suggest that medical staffs in China should pay more attention to metabolic syndrome in patients with psoriasis.

关 键 词：银屑病 代谢综合征 患病率 META分析 

分 类 号：R758.63[医药卫生—皮肤病学与性病学] R589[医药卫生—临床医学]