猪札幌病毒的研究进展  

Research progress on porcine sapovirus

作　　者：李晶娇[1] 沈权[2] 李饴 华修国[1] 

机构地区：[1]上海交通大学农业与生物学院,上海200240 [2]江苏大学医学院,镇江212013

出　　处：《微生物与感染》2016年第2期72-78,共7页Journal of Microbes and Infections

基　　金：国家自然科学基金(31270168;31402211)

摘　　要：猪札幌病毒(porcine sapovirus,PoSaV)是一种经粪-口途径传播引起猪急性胃肠炎的肠道病毒,对环境友好生态型养殖业构成一定威胁。研究表明,某些PoSaV与人SaV核苷酸序列具有很高的同源性,且越来越多来源于人和猪的SaV重组新毒株被发现,提示PoSaV具有跨种间感染及传播给人的潜在风险。迄今,PoSaV的入侵与感染、变异与迁移、免疫与致病、暴发与流行、跨种间感染与传播等机制尚不清楚。本文主要对PoSaV形态与抵抗力、基因组结构与功能、基因重组、传播方式、流行病学、受体等方面的研究进展进行综述。Porcine sapovirus（PoSaV）,transmitted through fecal-oral pathway,is an enteric calicivirus causing acute gastroenteritis in pigs,and poses a serious threat to the environment-harmony ecotype of breeding industry.Porcine sapoviruses closely related to human strains have been detected in swine.As more and more porcine and human recombinant sapoviruses have been reported,the potential risk of cross-species infections and zoonotic generation is a practical concern.However,researches on invasion,infection,mutation,migration,immunization,outbreaks,epidemiology,cross-species infection and transmission of porcine sapovirus are rare.In this review,we focus on viral morphology and resistance,genomic structure and recombinant,transmission,epidemiology and cell receptor of porcine sapovirus.

关 键 词：猪札幌病毒 跨种间感染 基因重组 受体 

分 类 号：S852.65[农业科学—基础兽医学]