经鼻蝶入路手术治疗儿童垂体瘤疗效及安全性评价  

Efficacy and Safety Evaluation of Surgical Treatment With Children With Pituitary Tumor

作　　者：邹彬[1] 杨刚[1] 周渝冬[1] 梁平[1] 

机构地区：[1]重庆医科大学附属儿童医院神经外科/儿童发育疾病省部共建教育部重点实验室/儿童发育重大疾病国家国际科技合作基地/儿科学重庆市重点实验室,400014

出　　处：《中国卫生标准管理》2016年第5期34-35,共2页China Health Standard Management

基　　金：国家临床重点专科建设项目资助(编号:国卫办医函[2013]544)

摘　　要：目的探讨经鼻蝶入路手术治疗儿童垂体瘤的临床疗效,并做安全性分析。方法选取我院儿童垂体瘤门诊患者22例,观察组:采用经鼻蝶入路切除术,对照组:采用翼点入路的经颅切除术,比较两种切除术的操作难度和临床疗效。并于患者出院后随访12个月,记录激素恢复率。结果经比较,观察组在手术时间、术中出血量、肿瘤全切率、术后住院观察期、激素恢复率、不良反应发生率等方面优于对照组,P<0.05。结论经鼻蝶的切除术具有可操作性、临床疗效确切、安全性高的优势。Objective To investigate the transsphenoidal approach surgery in the treatment of children with pituitary tumor clinical efficacy and safety analysis. Methods In our hospital pediatric pituitary tumor patient in 22 cases and observation group： the transsphenoidal approach resection,and the control group ：pterion approach transcranial resection,two resection operation difficulty and clinical curative effect. And in discharged patients were followed up for 12 months,recording the hormone recovery rate. Results The comparison of the observation group in the operation time,intraoperative blood loss,tumor resection rate,postoperative hospitalization period,hormone recovery rate,adverse reaction rate is better than that of the control group P〈0.05. Conclusion Transnasal sphenoid it has the advantages of operation,clinical curative effect and high safety.

关 键 词：儿童垂体瘤 疗效 安全性 

分 类 号：R651[医药卫生—外科学]