肾衰灵冲剂治疗慢性肾功能衰竭临床观察  

Clinical Observation of Combining Shenshuailing Electuary and Conventional Western Medicine to Treat Chronic Renal Failure

作　　者：殷再华 邓移安 

机构地区：[1]赤壁市中医医院肾内科,湖北赤壁437300

出　　处：《四川中医》2016年第4期77-79,共3页Journal of Sichuan of Traditional Chinese Medicine

摘　　要：目的：观察肾衰灵冲剂联合常规西药治疗慢性肾功能衰竭临床疗效。方法：选择我院2012年3月~2015年3月收治87例慢性肾功能衰竭患者作为研究对象,分为观察组（n=44）与对照组（n=43）。对照组静脉滴注舒血宁注射液,观察组加用肾衰灵冲剂,比较两组治疗前后中医证候积分、肾功能指标（Scr、Ccr）、治疗总有效率及安全性。结果：两组治疗前中医证候总积分的比较无统计学意义（P〉0.05）,治疗后两组积分均明显降低,组内前后差异有统计学意义（P〈0.05）,且观察组治疗后低于对照组,差异有统计学意义（P〈0.05）,提示该组积分下降幅度更大。两组治疗前Scr、Ccr的比较无统计学意义（P〉0.05）,治疗后两组Scr均降低、Ccr均升高,组内前后差异有统计学意义（P〈0.05）,同时观察组治疗后Scr低于对照组、Ccr高于对照组,差异有统计学意义（P〈0.05）,提示该组肾功能指标改善幅度更大。观察组治疗总有效率为81.8%（36/44）,明显高于对照组55.8%（24/43）,差异有统计学意义（P〈0.05）。结论：肾衰灵冲剂联合常规西药治疗慢性肾功能衰竭可有效改善患者症状及其肾功能,疗效佳,安全性高,具有较大临床应用价值。Objective： To observe the clinical curative effect of Shenshuailing Electuary combined with conventional western medicine in the treatment of chronic renal failure. Methods： 87 patients with chronic renal failure treated in our hospital during March 2012 to March 2015 were taken as the research objects and were divided into observation group（ n = 44） and controlled group（ n = 43）. The controlled group was intravenously injected with Shuxuening Injection while the observation group was additionally treated with Shenshuailing Electuary. The integral of TCM syndromes,renal function indexes（ Scr,Ccr）,total treatment efficiency and safety were compared between the two groups before and after the treatment. Results： There was no significant difference in the integral of TCM syndromes between the two groups before the treatment（ P〈0. 05）. After the treatment,the integrals of the two groups decreased significantly. There were statistically significant differences within the group before and after the treatment（ P〈0. 05）. After the treatment,the observation group was lower than the controlled group（ P〈0. 05）,which indicated that the decrease of the integral in the group was more significant. Before the treatment,the comparisons of Scr and Ccr between the two groups were not statistically significant（ P〉0. 05）. After the treatment,Scr in the two groups decreased and Ccr increased. There were statistically significant differences within the group before and after the treatment（ P〈0. 05）. Meanwhile,Scr in the observation group after the treatment was lower than that in the controlled group while Ccr was higher（ P〈0. 05）,which indicated that the improvement of renal function index in the group was more significant. The total effective rate of the observation group was 81. 8%（ 36 /44）,which was higher than 55. 8%（ 24 /43） of the controlled group（ P〈0. 05）. Conclusion： Shenshuailing Electuary combined with conventional western medicine in the treatment of chr

关 键 词：慢性肾功能衰竭 肾衰灵冲剂 脾肾衰败 

分 类 号：R692.5[医药卫生—泌尿科学]