福建省漳州市鼠类宿主感染广州管圆线虫调查  

Investigation on Angiostrongylus cantonensis Infection in Rodents in Zhangzhou City,Fujian Province

作　　者：林国华[1] 颜翠兰[1] 蔡茂荣[2] 黄明松[1] 周耀雄 方彦炎[3] 程由注[3] 

机构地区：[1]福建省龙海市疾病预防控制中心,龙海363100 [2]漳州市疾病预防控制中心,漳州363000 [3]福建省疾病预防控制中心,福州350001

出　　处：《中国寄生虫学与寄生虫病杂志》2016年第2期133-136,共4页Chinese Journal of Parasitology and Parasitic Diseases

基　　金：科技部自然资源平台项目(No.2005DKA21104);福建省卫生厅青年科研课题(No.2013-2-122)~~

摘　　要：目的 调查漳州市鼠类感染广州管圆线虫（Angiostrongylus cantonensis）的情况，为预防控制广州管圆线虫病提供科学依据。 方法 2013-2015年，按鼠类孳生环境选取漳州沿海（平原和丘陵组）和山区（丘陵和山地组）的4个县18个村，采用笼捕法捕鼠，鉴定鼠种、性别后，解剖心、肺，查找广州管圆线虫成虫，计算鼠类感染率，分析捕鼠点的不同自然生态环境与鼠类感染率的相关性。 结果 共捕获鼠类动物1 551只，分属黄胸鼠（Rattus flavipectus）、褐家鼠（R. norvegicus）、臭鼩鼱（Sorex araneus）、小家鼠（Mus musculus）和黄毛鼠（R. lossea），其中黄胸鼠最多，占41.8%（649/1 551），其次为褐家鼠和臭鼩鼱，分别占28.4%（441/1 551）和20.9%（324/1 551）。广州管圆线虫总感染率为9.2%（142/1 551），其中褐家鼠和黄胸鼠的感染率分别为13.2%（58/441）和11.4%（74/649），与臭鼩鼱［1.5%（5/323）］、小家鼠［1.4%（1/74）］和黄毛鼠［6.3%（4/63）］差异有统计学意义（P＜0.05）。沿海地区鼠类感染率为12.4%（83/668），明显高于山区的6.68%（59/883）（χ^2＝15.083，P＜0.05）。其中沿海平原组与沿海丘陵组感染率分别为12.7%（53/416）和11.9%（30/252），差异无统计学意义（P＞0.05）；山区丘陵组与山区山地组感染率分别为9.2%（46/499）和3.4%（13/384），差异有统计学意义（χ^2＝12.890，P＜0.05）。142只感染鼠共检获成虫696条，成虫主要寄生于肺动脉，占总虫数94.3%；其次为心脏，占总虫数5.7%。雄性与雌性鼠感染率分别为9.2%（73/795）和 9.1%（69/756），差异无统计学意义（P＞0.05）。 结论 黄胸鼠和褐家鼠为漳州市广州管圆线虫重要保虫宿主。各类生态环境鼠类的广州管圆线虫感染率有一定的差异。Objective To investigate the Angiostrongylus cantonensis infection in rodents in Zhangzhou City and provide basis for control the disease. Methods Eighteen villages in 4 counties, which located in coastal and mountain regions of rodent breeding, were selected between 2013-2015. Rodents were collected by cage trapping, and organs of heart and lungs were prepared for microscopic examination of A. cantonensis after identification of the species and age of the rodent. The infection rate was calculated and correlation between natural environment and the infection rate was analyzed. Results A total of 1 551 rodents were collected and identified to be Rattus flavipectus, R. norvegicus, Sorex araneus, Mus musculus and R. lossea with a high-to-low ranking of R. flavipectus（41.8%）, R. norvegicus（28.4%） and S. araneus（20.9%）. The overall infection mice was 9.2%（142/1 551）. The infection rates of R. norvegicus and R. flavipectus were 13.2%（58/441） and 11.4%（74/649） respectively, both significantly higher than that of Sorex araneus[1.5%（5/323）], Mus musculus[1.4%（1/74）] and R. lossea[6.3%（4/63）] （P〈0.05）. The infection rate in the costal regions was 12.4%（83/668）, significantly higher than that in the mountain regions（6.68%, 59/883）（χ^2=15.083, P〈0.05）. Moreover, in contrast with the significant difference in the infection rate between hilly（9.2%, 46/499） and mountainous areas（3.4%, 13/384）, there the infection rate showed no significant difference between coastal flatland（12.7%, 53/416） and coastal hilly areas（11.9%, 30/252） （χ^2=2.264, P〉0.05）. In addition, 696 adult worms were found in 142 infected rodents. These worms mainly located in the pulmonary artery（94.3%）, then and the heart （5.7%）. There was also no significant difference in infection rate between male（9.2%, 73/795） and female rodents（9.1%, 69/756） （P〉0.05）. Conclusion R. flavipectus and R. norvegicus are the important reservoir hosts for A. cantonensis in Zhangz

关 键 词：鼠类 生态环境 广州管圆线虫 感染率 

分 类 号：R383.1[医药卫生—医学寄生虫学]