中药配方颗粒剂配合维胺脂胶囊辨证分型治疗寻常痤疮60例疗效观察  

Clinical Observation of Chinese Medicine Formula Granules Combined with Viaminate Capsules in Differentiating Syndrome to Treat 60 Cases of Acne Vulgaris

作　　者：麻翱 麻林玖 

机构地区：[1]四川省广安市广安区人民医院皮肤科,四川广安638000

出　　处：《中国皮肤性病学杂志》2016年第5期517-519,共3页The Chinese Journal of Dermatovenereology

摘　　要：目的观察中药配方颗粒剂配合维胺脂胶囊辨证分型治疗寻常痤疮的临床疗效。方法将入选的120例寻常痤疮患者随机分成两组。治疗组60例,口服痤疮中药配方颗粒剂,并于饭后口服维胺脂胶囊50mg,均3次/d,同时外用异维A酸红霉素凝胶,每晚1次;对照组60例,仅予口服维胺脂胶囊和外用异维A酸红霉素凝胶,用法同治疗组。两组患者的疗程均为4周。结果治疗组有效率95.00%,对照组有效率63.33%,差异有统计学意义(P<0.01)。两组外用异维A酸红霉素凝胶后诉面部有不同程度的干燥、刺痛、鳞屑、潮红等不适,未见有胃肠道不良事件。结论中药配方颗粒配合维胺脂胶囊治疗寻常痤疮有效率高,服药方便,安全性好。Objective To observe the clinical effects of Chinese medicine formula granules combined with viaminate capsules in differentiating syndrome to treat acne vulgaris. Methods One hundred and twenty cases of acne vulgaris were randomly divided into treatment group and control group. The 60 cases of treatment group were instructed to take oral Chinese medicine formula granules and oral 50mg viaminate capsules after meal 3 times a day, and external use of different dimension isotretinoin erythromycin gel once every night. The 60 cases of control group were treated with oral viaminate capsules and external use of different dimension isotretinoin erythromycin gel only, with the same usage and dosage of the treatment group. The duration of treatment of the two groups were 4 weeks. Results The effective rate of treatment group was 95.00% compared to 63.33% of control group. There was significant difference between the two groups（P 〈 0. 01 ）. Following topical application of isotretinoin erythromycin gel, dry skin, sting, peeling, and erythema occurred on the face in both groups. No gastrointestinal adverse events were observed. Conclusion Chinese medi- cine formula granules combined with viaminate capsules in the treatment of acne vulgaris has the advantages of high efficiency, convenient use and good safety.

关 键 词：中药配方颗粒 维胺脂胶囊 辨证分型 寻常痤疮 疗效观察 

分 类 号：R758.733[医药卫生—皮肤病学与性病学]