The association between orthostatic hypertension and all-cause mortality in hospitalized elderly persons  

作　　者：Avraham Weiss Yichayaou Beloosesky Alon Grossman Agata Shlesinge Nira Koren-Morag Ehud Grossman 

机构地区：[1]Department of Geriatrics, Rabin Medical Center, Beilinson Hospital, Petach Tikvah, lsrael [2]Sackler Faculty of Medicine, Tel Aviv University, Israel [3]Department of Internal Medicine E, Rabin Medical Center, Beilinson Hospital, Petach Tikvah, lsrael [4]Department of Epidemiology and Preventive Medicine, Tel Aviv University, Israel [5]Internal Medicine Department and Hypertension Unit, Chaim Sheba Medical Center, Tel Hashomer, lsrael

出　　处：《Journal of Geriatric Cardiology》2016年第3期239-243,共5页老年心脏病学杂志（英文版）

摘　　要：Background Little is known about the prevalence oforthostatic hypertension （OHT） and its effect on long-term mortality in the eld- erly. We evaluated the prevalence of OHT and its effect on mortality in hospitalized elderly patients. Methods Out of 1852 patients admit- ted between 31/12/1999 and 31/12/2000 to an acute geriatric ward, 474 patients （48% males） with a mean age of 81.5 ±6.8 years were en- rolled in this study. Blood pressure （BP） was measured three times during the day in a supine and standing position. Patients with at least one increase in systolic or diastolic BP levels upon standing were diagnosed with OHT. Medical history, physical examination and laboratory parameters were retrieved from the medical records. Mortality data until 18th June 2014 were retrieved from the computerized system of the Ministry of the Interior. Results Four hundred and seven patients （86%） were diagnosed with OHT. Those without OHT had a lowerbody mass index and were more likely males, smokers, had a higher rate of Parkinson＇s disease and less congestive heart failure compared with those with OHT. Patients with OHT had a better survival rate than those without OHT （P = 0.024）. Hazard ratios （HRs） for mortality in those with OHT adjusted to age and multiple risk factors were： 0.67 [95% confidence interval （CI）： 0.51-0.87] and 0.73 （95% CI： 0.55-0.97）, respectively; a similar tendency was noticed in a sensitivity analysis by gender. Conclusion Hospitalized elderly patients with OHT had a better survival rate than those without OHT.

关 键 词：HYPERTENSION MORTALITY ORTHOSTATIC The elderly 

分 类 号：O212.1[理学—概率论与数理统计] TS218[理学—数学]