脂肪组织造血再生潜能的研究进展  

Progress of hematopoietic regenerative potential of adipose tissue

作　　者：李雪青[1,2] 唐锁勤[1] 栾佐[3] 

机构地区：[1]解放军总医院儿科,北京100853 [2]武警后勤学院附属医院儿科,天津300162 [3]海军总医院儿科,北京100048

出　　处：《国际儿科学杂志》2016年第4期303-306,共4页International Journal of Pediatrics

摘　　要：脂肪组织来源于中胚层，由脂肪细胞及基质血管成分组成。基质血管成分是一个尚未完全确定的细胞群，其中包含多种干／祖细胞。近来研究表明脂肪组织含有一定数量的造血干／祖细胞以维持其造血再生潜能，但具体调节机制目前尚不明确。现就脂肪组织及与骨髓微环境相似性研究进展作一综述，为认识脂肪组织的造血再生潜能提供新思路。Adipose tissue,derived from the mesoderm, consists of adipocytes and stromal vascular fraction. Stromal vascular fraction is a cell population that has not been fully identified, which contains a variety of stem/progenitor cells. Recent studies have indicated that adipose tissue contains a certain amount of hematopoiet- ic stem/progenitor cells to maintain its hematopoietic regeneration potential, but the specific mechanism of regu- lation is not clear yet. This review is mainly about the research progress of adipose tissue and its relationship with bone marrow microenvironment,providing a new idea for understanding the hematopoietic regeneration potential of adipose tissue.

关 键 词：脂肪组织 造血作用 再生 

分 类 号：R33[医药卫生—人体生理学]