成人正常肾脏体素内不相干运动扩散加权成像  

Intravoxei incoherent motion diffusion weighted imaging of normal adult kidney

作　　者：丁玉芹[1] 缪熙音[1] 李轫晨[1] 曹颖丽[1] 曾蒙苏[1] 周建军[1] 

机构地区：[1]复旦大学附属中山医院放射科上海市影像医学研究所复旦大学上海医学院影像学系,上海200032

出　　处：《实用放射学杂志》2016年第4期558-561,共4页Journal of Practical Radiology

摘　　要：目的 定量分析成人正常肾脏体素内不相干运动扩散加权成像（IVIM-DWI）参数特征，评估不同部位、性别和年龄对IVIM-DWI参数的影响。方法 招募30例健康成人志愿者行肾脏IVIM-DWI检查，2名影像医师分别测量双肾上极、中部和下极肾实质的D值、D＊值和f值。结果 成人正常肾脏中部的D值、D＊值和f值分别为（1.61±0.16）×10 -3 mm 2/s、（17.45±3.78）×10 -3 mm 2/s和（26.88±5.19）%。右肾的D值高于左肾（P〈0.05）。男性志愿者肾脏的f值高于女性（t=3.321，P=0.001）。正常肾脏＞50岁组的D值低于≤50岁组（t=3.548，P=0.001），年龄和D值呈负相关（r=-0.406）。2位观察者测量的D值、D＊值和f值的组内相关系数分别为0.881，0.56和0.741，肾脏中部IVIM-DWI各参数的一致性高于肾脏上极和下极。结论 成人正常肾脏IVIM-DWI参数受不同部位、性别和年龄的影响。Objective To analyze quantitatively intravoxel incoherent motion diffusion weighted imaging （IVIM-DWI） of normal adult kidney and to evaluate the effects of the location of the kidney, gender and age on IVIM-DWI parameters. Methods Thirty healthy adult volunteers were recruited to undergo IVIM-DWI examination. Two radiologists measured the D , D＊ and f values of renal parenchyma in both the upper pole, middle part and lower pole of the kidneys separately. Results The D , D＊ and f values of the middle part of kidneys in healthy adult were（ 1.61 ± 0.16 ）× 10^-3 mm^2/s, （ 17.45 ± 3.78）× 10^-3 mm^2/s and （ 26.88 ± 5.19 ） %, respectively. The D values of right kidney were higher than that of left kidney （P〈0.05}. The f values of normal kidney in male volunteers were higher than that of female （t = 3. 321 ,P=0. 001 ）. The D values of normal kidney in 〉50 years group were lower than that of 450 years group （t = 3. 548,P=0. 001）. D value of the kidney and age was negatively correlated （r=-0. 406）. Intraclass correlation coefficient of D, D＊ and f values between two observers were 0. 881,0.56 and 0. 741, respectively. The consistency of two observers in measurement of IVIM-DWI parameters in the middle part of kidneys was higher than that of the upper pole and lower pole of the kidneys. Conclusion The IVIM-DWI parameters of adult normal kidneys are influenced by different parts of the kidney,gender and age.

关 键 词：体素内不相干运动 扩散加权成像 成人 正常肾脏 

分 类 号：R322.61[医药卫生—人体解剖和组织胚胎学] R445.2[医药卫生—基础医学]