非体外循环下室壁瘤折叠术临床疗效的系统评价  

Clinical effcet of off- pump plication for left ventncu Iar aneurysm: system review

作　　者：王粮山 顾承雄[1] 李波[1] 李海涛[1] 刘长城[1] 

机构地区：[1]首都医科大学附属北京安贞医院-北京市心肺血管疾病研究所心脏外科六病房,100029

出　　处：《心肺血管病杂志》2016年第2期137-140,共4页Journal of Cardiovascular and Pulmonary Diseases

基　　金：“国家自然科学基金”(81370436);“北京市教委科技发展基金”(KZ201410025028);“北京市科技新星计划”(Z131107002213003)

摘　　要：目的:系统评价非体外循环(off-pump)下室壁瘤折叠术的临床疗效。方法:系统检索PUMED,中国期刊全文数据库(CNKI),万方数据库筛选与非体外循环下室壁瘤折叠术临床疗效的已发表文献。用R version 3.2.3软件进行荟萃分析。结果:共有8篇文献入选,8项研究off-pump下室壁瘤折叠术共491例,on-pump下室壁瘤线性切除108例,off-pump组近期死亡率的合成率为2.9%(95%CI:1.6%"4.6%),与off-pump组相比,近期病死率及重要并发症发生率均差异无统计学意义(RR=0.59,95%CI:0.12"2.98)及(RR=0.21,95%CI=0.04"1.16)。结论:目前的研究数据表明off-pump行室壁瘤折叠术是安全、有效及可行的,临床上应用仍需个体化治疗。Objective： To evaluate the survival Clinical effcet of off- pump plication for left ventncu Iar aneurysm. Methods： Using the PUMED,CNKI,WANFANG DATA,we reviewed all studies about Clinical effcet of off- pump plication for left ventncu Iar aneurysm. We searched for literature published before June 2015 and earlier. We used R version 3. 2. 3 and Stata / SE12. 0 to perform the statistical analysis. Results： A total of eight studies were identified including 599 patients with left ventncu Iar aneurysm who underwent off-pump（ n =491） and on-pump（ n = 108）. The pooled rate of in-hospital mortality was 2. 9%（ 95% CI： 1. 6% ＂4. 6%）.There was no significant difference in two groups in terms of in-hospital mortality（ RR = 0. 59,95% CI： 0. 12 ＂2. 98） or incidence of important complications（ RR = 0. 21,95% CI 0. 04 ＂1. 16）. Conclusion： The current data suggests that off-pump plication for left ventncu Iar aneurysm is feasible,safe and effective. However,the choice of treatment should be made on a case by case basis.

关 键 词：折叠术 心脏室壁瘤 系统评价 非体外循环 

分 类 号：R54[医药卫生—心血管疾病]