儿童和青少年直立性高血压伴血管迷走性晕厥、体位性心动过速综合征血流动力学反应的临床特征  被引量:12

Clinical characteristics of orthostatic hypertension with hemodynamic response of vasovagal syncope and postural orthostatic tachycardia syndrome in children and adolescents

在线阅读下载全文

作  者:邹润梅[1] 王成[1] 吴礼嘉[1] 罗雪梅[1] 林萍[1] 李芳[1] 谢振武[1] 

机构地区:[1]中南大学湘雅二医院儿童医学中心儿童心血管专科,长沙410011

出  处:《中华儿科杂志》2016年第4期264-268,共5页Chinese Journal of Pediatrics

基  金:湖南省发展改革委员会课题[湘财企指(2015)83号]

摘  要:目的分析儿童和青少年直立性高血压(OHT)伴血管迷走性晕厥(VVS)、体位性心动过速综合征(POTS)血流动力学反应的临床特征。方法选取2008年7月至2015年4月在中南大学湘雅二医院儿童晕厥专科就诊的儿童和青少年病例,根据直立倾斜试验(HUTT)结果分为3组:OHT组(单纯OHT)、OHT+VVS组(OHT伴VVS血流动力学反应)、OHT+POTS组(OHT伴POTS血流动力学反应),分析其临床特征。结果纳入629例经Hu_rr诊断为OHT的病例,OHT组300例,OHT+VVS组264例,OHT+POTS组65例。三组患儿以晕厥、头晕为主要症状,且OHT+VVS组以晕厥为主要症状的患儿比例明显多于OHT组(49.6%比35.7%,X^2=11.211,P〈0.05)和OHT+POTS组(49.6%比27.7%,X。=10.123,P〈0.05)。OHT+VVS组基线心率(HR)[(78±14)次/min比(77±12)次/min,t=2.570,P〈0.05]、HuTT3min时HR[(100±14)次/min比(94±13)次/min,t=17.464,P〈0.05]、HuTT3rain时HR与基线HR差值(AHR)[(22±12)次/min比(17±9)次/min,t=19.303,P〈0.05]明显高于OHT组。OHT+POTS组基线收缩压(SBP)[(105±10)mmHg比(103±10)mmHg(1mmHg=0.133kPa),t=4.918,P〈0.05]、HUTY 3min时SBP[(114±10)mmHg比(113±11)mmHg,t=4.046,P〈0.05]、基线舒张压(DBP)[(64±6)mmHg比(63±7)mmHg,t=2.618,P〈0.05]、HuTT3rain时DBP[(784-8)mmHg比(774-8)mmHg,t=3.302,P〈0.05]、HUTT3min时HR[(107±14)次/min比(94±13)次/min,t=24.229,P〈0.05]及AHR[(32±11)次/rain比(17±9)次/min,t=39.146,P〈0.05]明显高于OHT组,而基线HR[(75±14)次/min比(77±12)次/min,t=4.221,P〈0.05]明显低于OHT组。结论卧位、立位HR较快,HR改变较大的OHT更易合并VVS;卧位及立位SBP和DBP均较高,而卧位HR较低的OHT患者更易合并POTS。Objective To analyze the clinical characteristics of orthostatie hypertension (OHT) with hemodynamic response of vasovaga] syncope (VVS) and postural orthostatic taehycardia syndrome (POTS) in children arid adolescents. Method Children and adolescents admitted to the Second Xiangya Hospital from July 2008 to April 2015 were included, and divided into three groups according to the results of head-up tilt test (HUTT): OHT group, OHT ± VVS group, OHT ± POTS group. The clinical characteristics were analyzed. Result Totally 629 cases were included, 300 cases in OHT group, 264 cases in OHT ± VVS group and 65 cases in OHT ± POTS group. Syncope and dizziness were the main symptoms of the three groups, and the proportion of patients complaining syncope in OHT ± VVS group was higher than that in OHT group (49.6% vs. 35.7% , X2 =11.211 , P〈0.05) and in OHT ± POTS group (49.6% vs.27.7%, x2 = 10. 123, P 〈0.05). Baseline heart rate (HR) ( (78 ± 14) beat/min vs. (77 ± 12) beat/ min, t = 2. 570, P 〈 0.05 ), HUTT 3 min HR ( ( 100 ± 14) beat/min vs. (94± 13) beat/min, t = 17. 464, P 〈 0.05) and AHR ( (22 ± 12) beat/min vs. ( 17 ± 9) beat/min, t =19. 303, P 〈 0.05 ) were higher in OHT ± VVS group than in OHT group. When compared with OHT group, baseline systolic blood pressure (SBP) ((105±10) mmHg(1 mmHg=0.133 kPa) vs. (103-±10) mmHg, t=4.918, P〈0.05), HUTT 3 minSBP((114±10) mmHgvs. (113±11) mmHg, t =4.046, P〈0.05), baseline diastolic blood pressure (DBP)((64±6) mmHg vs. (63±7) mmHg, t=2.618, P〈0.05), HUTT3 min DBP((78± 8) mmHgvs. (77±8) mmHg, t=3.302, P〈0.05), HUTT3 minHR ((107±14) beat/minvs. (94± 13) beat/min, t = 24. 229, P 〈 0.05) and AHR ( (32 _± 11 ) beat/min vs. ( 17 ± 9) beat/min, t = 39. 146, P 〈 0.05 ) in OHT ± POTS group were significantly higher, and baseline HR ( (75 ± 14) beat/min vs. (77 ± 12) beat/min, t = -

关 键 词:晕厥 血管迷走神经性 直立耐受不能 体位性心动过速综合征 儿童 

分 类 号:R725.4[医药卫生—儿科]

 

参考文献:

正在载入数据...

 

二级参考文献:

正在载入数据...

 

耦合文献:

正在载入数据...

 

引证文献:

正在载入数据...

 

二级引证文献:

正在载入数据...

 

同被引文献:

正在载入数据...

 

相关期刊文献:

正在载入数据...

相关的主题
相关的作者对象
相关的机构对象