急性酒精中毒对大鼠溺死后肺组织硅藻检出的影响  

Influence of acute alcohol intoxication on drowning rat lung after diatom detection

作　　者：伊吉普[1] 牛真珍 万勇[1] 张岳灿[1] 问腾飞 喻林升[4] 叶光华[4] 楼迪栋[5] 

机构地区：[1]宁波卫生职业技术学院,浙江宁波315100 [2]宁波鄞州人民医院,浙江宁波315100 [3]宁波天童司法鉴定所,浙江宁波315100 [4]温州医科大学,浙江温州325035 [5]贵阳医学院法医学研究室,贵州贵阳550000

出　　处：《中国法医学杂志》2016年第2期137-139,共3页Chinese Journal of Forensic Medicine

基　　金：宁波卫生职业技术学院校级科研计划项目(2014Y15)

摘　　要：目的急性酒精中毒对大鼠溺死后肺组织硅藻检出的影响。方法将40只大鼠随机分为5组,进行酒精灌胃,灌注量分别为:正常组(0m L/kg)、低剂量组(7m L/kg)、中剂量组(15m L/kg)、高剂量组(22m L/kg)、死后抛尸组(0m L/kg)。观察各组大鼠行为变化、溺水时生存能力及死后肺组织中硅藻检出量。结果高剂量组呼吸出现浅慢,呼吸停止时间减少(P<0.05)。酒精灌注各组大鼠攀附时间均减少(P<0.05),肺组织硅藻检出量均减少(P<0.05)。结论急性酒精中毒可以导致大鼠溺死后肺组织硅藻检出量减少。Objective To investigate the influence of acute alcohol intoxication on drowning rat lung after diatom detection. Methods 40 rats were randomly divided into five groups. The alcohol perfusion in each group was： normal group（ 0mL / kg）,low-dose group（ 7mL / kg）,middle-dose group（ 15 mL / kg）,high-dose group（ 22 mL / kg）,postmortem submersion group（ 0mL / kg）. Observe the changes of behavior,drowning survival ability and the diatom content in lung tissue with each group postmortem rats after intragastric administration of alcohol. Results Compared with the normal group,rats in high dose group breathed more slowly than in low-dose group,and the apnea time was reduced（ P〈0. 05）. The climbing time was decreased and the diatom content in lung tissue was also decreased in each group rats with alcohol perfusion（ P〈0. 05）. Conclusion The diatom content in lung tissue was reduced in rats with acute alcohol intoxication after drowning.

关 键 词：法医病理学 急性酒精中毒 溺水 硅藻 

分 类 号：D919[医药卫生—法医学]