从心肾论治轻度认知损害中医综合治疗方案的临床疗效评价研究  

Evaluation on the Clinical Effect of Traditional Chinese Medicine Comprehensive Treatment on Mild Cognitive Impairment from the Heart and Kidney

作　　者：刘寅[1] 项颗[1] 孙莉[1] 

机构地区：[1]吉林省中医药科学院第一临床医院,长春130021

出　　处：《中国中医药现代远程教育》2016年第7期59-61,共3页Chinese Medicine Modern Distance Education of China

基　　金：吉林省中医药管理局重点课题项目(No:2014-ZD1)

摘　　要：目的评价从心肾论治轻度认知损害中医综合治疗方案的临床疗效及其优势。方法应用随机数字表法将符合纳入标准的180例患者随机分为治疗组(130例)与对照组(50例);治疗组依据治疗方案分为治疗组A(单纯中药组)、治疗组B(中药汤剂+一种中医特色疗法)、治疗组C(中药汤剂+两种或两种以上中医特色疗法),两组均给予控制高血压、高血糖、高血脂等原发病的基础治疗,同时治疗组辨证采用中药配合针刺、推拿、中药熏蒸等中医特色疗法。结果治疗组中医证候积分及ADAS-COG-DVR降低,MMSE评分增高,差异有统计学意义(P<0.05),且优于对照组(P<0.05);治疗组C与治疗组A、B治疗第6周后比较,中医证候积分及ADAS-COG-DVR降低,MMSE评分增高,差异均有统计学意义(P<0.05),治疗第12周后比较差异均无统计学意义(P>0.05);治疗组IADL评分较治疗前降低,对照组无明显改变,但两组治疗前后及组间比较差异无统计学意义(P>0.05)。结论 :从心肾论治轻度认知损害中医综合治疗方案临床疗效优势显著,选择适宜的中医综合治疗方案较单纯药物治疗可以缩短轻度认知损害治疗周期,值得进一步推广应用。Objective To evaluate the clinical effect and advantages of traditional Chinese medicine comprehensive treatment on mild cognitive impairment from the heart and kidney. Methods 180 cases of patients who met the criteria were randomly divided into treatment group（130 cases） and control group（50 cases）. The treatment group according to the treatment plan was divided into treatment group A（Chinese medicine group）, treatment group B（Chinese medicine decoction and a TCM therapy） and treatment group C（Chinese medicine decoction and two or more than two kinds of TCM therapy）. The two groups were given basic treatment and control of hypertension, high blood sugar, high blood lipids and other primary diseases, while the treatment group used traditional Chinese medicine syndrome differentiation combined with acupuncture and massage, herbal fumigation therapy of Chinese medicine.Results TCM syndrome score and ADAS-COG-DVR in the treatment group were significantly higher than those of the control group（P0.05）, and the difference was statistically significant（ P0.05）. Treatment group C and treatment group A, B after sixth weeks of treatment, TCM syndrome score and-COG-DVR ADAS decreased, MMSE score increased, and the difference was statistically sig-nificant（P0.05）. After twelfth weeks of treatment, the differences were not statistically significant（ P0.05）. The IADL score of the treatment group was lower than that before treatment, the control group had no significant change, but there was no significant difference between the two groups before and after treatment and between groups（ P〈0.05）. Conclusion The traditional Chinese medicine comprehensive treatment on mild cognitive impairment from the heart and kidney has significant advantage, the choice of appropriate treatment of traditional Chinese medicine can shorten the treatment period of mild cognitive impairment, and is worthy of further popularization and application.

关 键 词：心肾论治 轻度认知损害 中医综合治疗方案 临床疗效评价 

分 类 号：R277.7[医药卫生—中医学]